Advances in the prevention and treatment of obesity-driven effects in breast cancers

K Chen, J Zhang, NM Beeraka, C Tang… - Frontiers in …, 2022 - frontiersin.org
Obesity and associated chronic inflammation were shown to facilitate breast cancer (BC)
growth and metastasis. Leptin, adiponectin, estrogen, and several pro-inflammatory …

Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention

M Picon‐Ruiz, C Morata‐Tarifa… - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE Recent decades have seen an unprecedented rise in
obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than …

The impact of obesity on breast cancer

DF Argolo, CA Hudis, NM Iyengar - Current oncology reports, 2018 - Springer
The rates of obesity are increasing worldwide and this condition is now recognized as a
leading preventable cause of cancer. Several diseases are directly related to obesity …

The obesity-breast cancer link: a multidisciplinary perspective

EN Devericks, MS Carson, LE McCullough… - Cancer and Metastasis …, 2022 - Springer
Obesity, exceptionally prevalent in the USA, promotes the incidence and progression of
numerous cancer types including breast cancer. Complex, interacting metabolic and …

Role of adipokines and cytokines in obesity-associated breast cancer: therapeutic targets

S Khan, S Shukla, S Sinha, SM Meeran - Cytokine & growth factor reviews, 2013 - Elsevier
Obesity is the cause of a large proportion of breast cancer incidences and mortality in post-
menopausal women. In obese people, elevated levels of various growth factors such as …

Obese adipose tissue as a driver of breast cancer growth and development: update and emerging evidence

P Bhardwaj, KA Brown - Frontiers in Oncology, 2021 - frontiersin.org
Obesity is an established risk factor for breast cancer growth and progression. A number of
advances have been made in recent years revealing new insights into this link. Early events …

Obesity and inflammation: new insights into breast cancer development and progression

NM Iyengar, CA Hudis, AJ Dannenberg - American Society of Clinical …, 2013 - ascopubs.org
The importance of inflammation in promoting carcinogenesis and tumor progression is well
recognized. Chronic inflammation caused by a variety of infectious agents can lead to the …

Obesity and breast cancer prognosis: weight of the evidence

FA Sinicrope, AJ Dannenberg - Journal of clinical oncology, 2011 - ascopubs.org
The percentage of overweight and obese adults and children has been steadily increasing
during the last two decades, and it is estimated that one third of US adults are obese. 1 …

Metabolic pathways in obesity-related breast cancer

KA Brown - Nature Reviews Endocrinology, 2021 - nature.com
This Review focuses on the mechanistic evidence for a link between obesity, dysregulated
cellular metabolism and breast cancer. Strong evidence now links obesity with the …

The many faces of obesity and its influence on breast cancer risk

T Agurs-Collins, SA Ross, BK Dunn - Frontiers in oncology, 2019 - frontiersin.org
Obesity is associated with increased risk of breast and other cancers. However, the
complexity of the underlying mechanisms, together with the interplay of diet and physical …