Pyronaridine protects against SARS-CoV-2 infection in mouse
There are currently relatively few small-molecule antiviral drugs that are either approved or
emergency-approved for use against severe acute respiratory coronavirus 2 (SARS-CoV-2) …
emergency-approved for use against severe acute respiratory coronavirus 2 (SARS-CoV-2) …
Pyronaridine and artesunate are potential antiviral drugs against COVID-19 and influenza
JY Bae, GE Lee, H Park, J Cho, YE Kim, JY Lee, C Ju… - bioRxiv, 2020 - biorxiv.org
Since the first human case was reported in Wuhan Province, China in December 2019,
SARS-CoV-2 has caused millions of human infections in more than 200 countries worldwide …
SARS-CoV-2 has caused millions of human infections in more than 200 countries worldwide …
Pyronaridine tetraphosphate is an efficacious antiviral and anti-inflammatory active against multiple highly pathogenic coronaviruses
J Ardanuy, R Johnson, C Dillen, L Taylor, H Hammond… - Mbio, 2023 - Am Soc Microbiol
ABSTRACT The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), continues to be one of the largest …
respiratory syndrome coronavirus-2 (SARS-CoV-2), continues to be one of the largest …
Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms
Severe acute respiratory coronavirus 2 (SARS-CoV-2) is a newly identified virus that has
resulted in over 2.5 million deaths globally and over 116 million cases globally in March …
resulted in over 2.5 million deaths globally and over 116 million cases globally in March …
[HTML][HTML] Anthracyclines inhibit SARS-CoV-2 infection
Z Wang, Q Pan, L Ma, J Zhao, F McIntosh, Z Liu, S Ding… - Virus Research, 2023 - Elsevier
Vaccines and drugs are two effective medical interventions to mitigate SARS-CoV-2
infection. Three SARS-CoV-2 inhibitors, remdesivir, paxlovid, and molnupiravir, have been …
infection. Three SARS-CoV-2 inhibitors, remdesivir, paxlovid, and molnupiravir, have been …
Compounds with therapeutic potential against novel respiratory 2019 coronavirus
MA Martinez - Antimicrobial agents and chemotherapy, 2020 - Am Soc Microbiol
Currently, the expansion of the novel human respiratory coronavirus (known as SARS-CoV-
2 [severe acute respiratory syndrome coronavirus 2], COVID-2019 [coronavirus disease …
2 [severe acute respiratory syndrome coronavirus 2], COVID-2019 [coronavirus disease …
Discovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cells
X Nguyenla, E Wehri, E Van Dis, SB Biering… - Scientific reports, 2022 - nature.com
Abstract SARS coronavirus 2 (SARS-CoV-2) has caused an ongoing global pandemic with
significant mortality and morbidity. At this time, the only FDA-approved therapeutic for COVID …
significant mortality and morbidity. At this time, the only FDA-approved therapeutic for COVID …
[HTML][HTML] Therapeutic efficacy of an oral nucleoside analog of remdesivir against SARS-CoV-2 pathogenesis in mice.
A Schäfer, DR Martinez, JJ Won, FR Moreira, AJ Brown… - BioRxiv, 2021 - ncbi.nlm.nih.gov
The COVID-19 pandemic remains uncontrolled despite the rapid rollout of safe and effective
SARS-CoV-2 vaccines, underscoring the need to develop highly effective antivirals. In the …
SARS-CoV-2 vaccines, underscoring the need to develop highly effective antivirals. In the …
Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice
The coronavirus disease 2019 (COVID-19) pandemic remains uncontrolled despite the
rapid rollout of safe and effective severe acute respiratory syndrome coronavirus 2 (SARS …
rapid rollout of safe and effective severe acute respiratory syndrome coronavirus 2 (SARS …
The preclinical inhibitor GS441524 in combination with GC376 efficaciously inhibited the proliferation of SARS-CoV-2 in the mouse respiratory tract
Y Shi, L Shuai, Z Wen, C Wang, Y Yan… - Emerging Microbes & …, 2021 - Taylor & Francis
The unprecedented coronavirus disease 2019 (COVID-19) pandemic, caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a serious threat to global public …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a serious threat to global public …