The highly specific induction of RNA interference-mediated gene knockdown, based on the direct application of small interfering RNAs (siRNAs), opens novel avenues towards …
Through a mechanism known as RNA interference (RNAi), small interfering RNA (siRNA) molecules can target complementary mRNA strands for degradation, thus specifically …
MA Subhan, VP Torchilin - Nanomedicine: Nanotechnology, Biology and …, 2020 - Elsevier
Gene silencing by RNA interference represents a promising therapeutic approach. The development of carriers, eg, polymers, lipids, peptides, antibodies, aptamers, small …
B Hu, Y Weng, XH Xia, X Liang… - The journal of gene …, 2019 - Wiley Online Library
Small interfering RNA (siRNA) enables efficient target gene silencing by employing a RNA interference (RNAi) mechanism, which can compromise gene expression and regulate gene …
W Alshaer, H Zureigat, A Al Karaki, A Al-Kadash… - European journal of …, 2021 - Elsevier
Owing to specific and compelling gene silencing, RNA interference (RNAi) is expected to become an essential approach in treating a variety of infectious, hemato-oncological …
PE Saw, EW Song - Science China Life Sciences, 2020 - Springer
Since the revolutionary discovery of RNA interference (RNAi), a remarkable progress has been achieved in understanding and harnessing gene silencing mechanism; especially in …
RNA interference (RNAi) is a well-conserved, ubiquitous, endogenous mechanism that uses small noncoding RNAs to silence gene expression. The endogenous small RNAs, called …
D Cejka, D Losert, V Wacheck - Clinical science, 2006 - portlandpress.com
Gene silencing by siRNA (short interfering RNA) is a still developing field in biology and has evolved as a novel post-transcriptional gene silencing strategy with therapeutic potential …
Y Higuchi, S Kawakami, M Hashida - BioDrugs, 2010 - Springer
RNA interference (RNAi) is a post-transcriptional gene-silencing mechanism that involves the degradation of messenger RNA in a highly sequence-specific manner. Double-stranded …