Type 1 diabetes is a chronic disease caused by autoimmune destruction of pancreatic β
cells. Individuals with type 1 diabetes are reliant on insulin for survival. Despite enhanced …

Type 1 diabetes is a chronic autoimmune disease characterised by insulin deficiency and
resultant hyperglycaemia. Knowledge of type 1 diabetes has rapidly increased over the past …

With the conceptual advance about four decades ago that type 1 diabetes represents an
autoimmune disease, hope arose that immune-based therapies would soon emerge to …

Type 1 diabetes results from the autoimmune destruction of insulin-producing β cells in the
pancreas. Genetic and, as yet undefined, environmental factors act together to precipitate …

Type 1 diabetes is an autoimmune disease caused by the immune-mediated destruction of
pancreatic β cells that results in lifelong absolute insulin deficiency. For nearly a century …

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Type 1 diabetes is one of the most common chronic childhood illnesses, affecting 18 to 20
per 100000 children a year in the United Kingdom. 1 The American Diabetes Association …

In type 1 diabetes, insulin remains the mature therapeutic cornerstone; yet, the increasing
number of individuals developing type 1 diabetes (predominantly children and adolescents) …

Type 1 diabetes mellitus (T1DM) is an autoimmune disorder directed against the β cells of
the pancreatic islets. The genetic risk of the disease is linked to HLA-DQ risk alleles and …

Type 1 diabetes (T1D) is a chronic autoimmune disease in which destruction or damaging of
the beta-cells in the islets of Langerhans results in insulin deficiency and hyperglycemia. We …