Background During the course of adulthood and aging, white matter (WM) structure and
organization are characterized by slow degradation processes such as demyelination and …

Major depressive disorder (MDD), schizophrenia (SCZ) and bipolar disorder (BP) are
common, disabling and heritable psychiatric diseases with a complex overlapping polygenic …

Abstract Background Aging and Alzheimer's disease (AD) are associated with alterations in
the brain's white matter (WM) microstructure. AD also exhibits significant sex differences …

BACKGROUND: Postmortem and volumetric imaging data suggest that brain myelination is
a dynamic lifelong process that, in vulnerable late-myelinating regions, peaks in middle age …

The macro-and microstructural architecture of human brain white matter undergoes
substantial alterations throughout development and ageing. Most of our understanding of …

Unveiling the details of white matter (WM) maturation throughout ageing is a fundamental
question for understanding the ageing brain. In an extensive comparison of brain age …

During aging, human white matter (WM) is subject to dynamic structural changes which have
a deep impact on healthy and pathological evolution of the brain through the lifespan; …

This meta-analysis and systematic review synthesized data from 30 longitudinal diffusion
tensor imaging (DTI) studies on the magnitude, direction, spatial patterns, and modifiers of …

Quantifying the microstructural properties of the human brain's connections is necessary for
understanding normal ageing and disease states. We examined brain white matter MRI data …

A comprehensive characterization of the brain's white matter is critical for improving our
understanding of healthy and diseased aging. Here we used diffusion-weighted magnetic …