Anemia is very common in patients with inflammatory disorders. Its prevalence is associated
with severity of the underlying disease, and it negatively affects quality of life and cardio …

Iron is vital for a vast variety of cellular processes and its homeostasis is strictly controlled
and regulated. Nevertheless, disorders of iron metabolism are diverse and can be caused …

BACKGROUND: The most frequent clinical condition exemplifying the interplay between
iron and immune function is the anemia of chronic disease (ACD). METHODS: Based on a …

Anemia in the setting of chronic inflammatory disorders is a very frequent clinical condition,
which is, however, often neglected or not properly treated given the problems often caused …

Anemia of inflammation (AI) is a highly prevalent comorbidity in patients affected by chronic
inflammatory disorders, such as chronic kidney disease, inflammatory bowel disease, or …

Iron deficiency and immune activation are the two most frequent causes of anemia, both of
which are based on disturbances of iron homeostasis. Iron deficiency anemia results from a …

Iron is an essential compound for immunosurveillance because of its growth-promoting and
differentiation-inducing properties for immune cells and its interference with cell-mediated …

Anemia of chronic inflammation (ACI) is a frequently diagnosed anemia and portends an
independently increased morbidity and poor outcome associated with multiple underlying …

Iron and its homeostasis are intimately tied to the inflammatory response. The adaptation to
iron deficiency, which confers resistance to infection and improves the inflammatory …

Anemia of chronic disease, also called anemia of inflammation, is characterized by
hypoferremia due to iron sequestration that eventually results in iron-restricted …