Liver fibrosis is a fibrogenic and inflammatory process that results from hepatocyte injury and
is characterized by hepatic architectural distortion and resultant loss of liver function. There …

Liver fibrosis represents a common outcome of most chronic liver diseases. Advanced
fibrosis leads to cirrhosis for which no effective treatment is available except liver …

Liver fibrosis is the end-stage of many chronic liver diseases and is a significant health
threat. The only effective therapy is liver transplantation, which still has many problems …

The liver is an organ with impressive regenerative potential and has been shown to heal
sizable portions after their removal. However, certain diseases can overstimulate its …

The limited availability of organs for liver transplantation, the ultimate curative treatment for
end stage liver disease, has resulted in a growing and unmet need for alternative therapies …

Liver fibrosis is a common result of most chronic liver diseases, and advanced fibrosis often
leads to cirrhosis. Currently, there is no effective treatment for liver cirrhosis except liver …

Progressive liver fibrosis is a major health issue for which no effective treatment is available,
leading to cirrhosis and orthotopic liver transplantation. However, organ shortage is a reality …

Hepatic fibrosis/cirrhosis is a significant health burden worldwide, resulting in liver failure or
hepatocellular carcinoma (HCC) and accounting for many deaths each year. The …

Mesenchymal stem cell (MSC) transplantation is a novel treatment for liver diseases due to
the roles of MSCs in regeneration, fibrosis inhibition and immune regulation. However, the …

Unbalanced immune cell populations or immune cell infiltration of the liver can disrupt the
immune-privileged state of the liver, resulting in liver injury or fibrosis. Therefore, the …