Cell membrane‐bound serine proteases are important in the maintenance of physiological
homeostasis. Hepsin is a type II transmembrane serine protease highly expressed in the …

Hepsin is a transmembrane serine protease primarily expressed in the liver. To date, the
physiological function of hepsin remains poorly defined. Here we report that hepsin-deficient …

Hepsin is a transmembrane serine protease implicated in many biological processes,
including hepatocyte growth, urinary protein secretion, auditory nerve development, and …

Hepsin belongs to a family of cell-surface serine proteases, which have sparked interest as
therapeutic targets because of the accessibility of extracellular protease domain for …

Hepsin is a membrane-anchored, trypsin-like serine protease with prominent expression in
the human liver and tumours of the prostate and ovaries. To better understand the biological …

Hepsin is a type II transmembrane serine protease that is expressed in normal liver, and at
lower levels in kidney, pancreas, and testis. Several studies have shown that hepsin mRNA …

The hepsin gene encodes a type II transmembrane serine protease. Previous studies have
shown the overexpression of hepsin in prostate cancer, and the dysregulation of hepsin …

Hepsin, a type II transmembrane serine protease, is commonly overexpressed in prostate
and breast cancer. The hepsin protein is stabilized by the Ras‐MAPK pathway, and …

Type II transmembrane serine proteases (TTSPs), including hepsin, are a new class of cell
surface catalytic enzymes. In the present study, a non-transmembrane isoform of hepsin …

Hepsin is a type II transmembrane serine protease overexpressed in the majority of human
prostate cancers. We recently demonstrated that hepsin promotes prostate cancer …