Stress affects a constellation of physiological systems in the body and evokes a rapid shift in
many neurobehavioral processes. A growing body of work indicates that the …

The endocannabinoid system is a widely distributed, neuromodulatory system which serves
an integral role in regulating synaptic transmission. The presence of this system in stress …

Endogenous cannabinoids play an important role in the physiology and behavioral
expression of stress responses. Activation of the hypothalamic–pituitary–adrenal (HPA) axis …

Endocannabinoid signaling is distributed throughout the brain, regulating synaptic release
of both excitatory and inhibitory neurotransmitters. The presence of endocannabinoid …

Secretion of glucocorticoid hormones during stress produces an array of physiological
changes that are adaptive and beneficial in the short term. In the face of repeated stress …

Accumulating evidence over the past decade has highlighted an important role of the
endocannabinoid (eCB) system in the regulation of stress and emotional behavior across …

The endocannabinoid signaling system (ECSS) is altered by exposure to stress and
mediates and modulates the effects of stress on the brain. Considerable preclinical data …

The endocannabinoid system is a neuroactive lipid signaling system that functions to gate
synaptic transmitter release. Accumulating evidence has demonstrated that this system is …

The endocannabinoid system is widely expressed in the limbic system, prefrontal cortical
areas, and brain structures regulating neuroendocrine stress responses, which explains the …

The endocannabinoid system has recently emerged as a vital component of the stress
response and is an appealing target for the treatment of mood and anxiety disorders …