[HTML][HTML] Host genetic factors determining COVID-19 susceptibility and severity

TP Velavan, SR Pallerla, J Rüter, Y Augustin… - …, 2021 - thelancet.com
The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2
(SARS-CoV-2) poses an unprecedented challenge to humanity. SARS-CoV-2 infections …

[HTML][HTML] Clinical implications of host genetic variation and susceptibility to severe or critical COVID-19

CI van der Made, MG Netea, FL van der Veerdonk… - Genome Medicine, 2022 - Springer
Since the start of the coronavirus disease 2019 (COVID-19) pandemic, important insights
have been gained into virus biology and the host factors that modulate the human immune …

Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity

K Gupta, G Kaur, T Pathak, I Banerjee - Gene, 2022 - Elsevier
The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …

[HTML][HTML] Human genetic factors associated with susceptibility to SARS-CoV-2 infection and COVID-19 disease severity

C Anastassopoulou, Z Gkizarioti, GP Patrinos… - Human genomics, 2020 - Springer
Background The emergence of the novel coronavirus in Wuhan, Hubei Province, China, in
December 2019 marked the synchronization of the world to a peculiar clock that is counting …

The role of host genetics in susceptibility to severe viral infections in humans and insights into host genetics of severe COVID-19: A systematic review

A Elhabyan, S Elyaacoub, E Sanad, A Abukhadra… - Virus research, 2020 - Elsevier
Background Susceptibility to severe viral infections was reported to be associated with
genetic variants in immune response genes using case reports and GWAS studies. SARS …

[HTML][HTML] The human genetic epidemiology of COVID-19

MEK Niemi, MJ Daly, A Ganna - Nature Reviews Genetics, 2022 - nature.com
Human genetics can inform the biology and epidemiology of coronavirus disease 2019
(COVID-19) by pinpointing causal mechanisms that explain why some individuals become …

[HTML][HTML] Genetics insight for COVID-19 susceptibility and severity: a review

I Fricke-Galindo, R Falfán-Valencia - Frontiers in immunology, 2021 - frontiersin.org
Coronavirus disease (COVID-19) presents a broad spectrum of clinical manifestations
ranging from an asymptomatic to a severe clinical course. The host genetic background …

[HTML][HTML] Immunogenetic association underlying severe COVID-19

K McCoy, A Peterson, Y Tian, Y Sang - Vaccines, 2020 - mdpi.com
SARS-CoV2 has caused the current pandemic of new coronavirus disease 2019 (COVID-
19) worldwide. Clinical outcomes of COVID-19 illness range broadly from asymptotic and …

[HTML][HTML] Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection

SMA Hashemi, M Thijssen, SY Hosseini, A Tabarraei… - Archives of …, 2021 - Springer
The SARS-CoV-2 pandemic has become one of the most serious health concerns globally.
Although multiple vaccines have recently been approved for the prevention of coronavirus …

An overview of human proteins and genes involved in SARS-CoV-2 infection

Z Jahanafrooz, Z Chen, J Bao, H Li, L Lipworth, X Guo - Gene, 2022 - Elsevier
As of July 2021, the outbreak of coronavirus disease 2019 (COVID-19), caused by SARS-
CoV-2, has led to more than 200 million infections and more than 4.2 million deaths globally …