Background: A recently developed urinary peptidomics biological aging clock can be used
to study accelerated human aging. From 1990 to 2019, exposure to airborne particulate …

Background Exposure to air pollution has been associated with cardiorespiratory morbidity
and mortality. However, the chemical constituents and pollution sources underlying these …

Evidence on the effects of internal chemical mixture exposures on biological age is limited. It
also remains unclear whether hormone homeostasis and lifestyle factors can modify such a …

Background: Few studies have been performed on pulmonary effects of air pollution in the
elderly—a vulnerable population with low reserve capacity—and mechanisms and …

Mitochondrial DNA (mtDNA) content and telomere length are putative aging biomarkers and
are sensitive to environmental stressors, including pollutants. Our objective was to identify …

Background: Telomere length and mitochondrial DNA (mtDNA) content are markers of aging
and aging-related diseases. There is inconclusive evidence concerning the mechanistic …

Summary Background The Global Burden of Diseases, Injuries, and Risk Factors Study
2019 called for innovation in addressing age-related disabilities. Our study aimed to identify …

Abstract Background Physical functional limitations (PFLs) increase the vulnerability of
adults, but their pathogenesis remains unclear. Methods We conducted a nationwide …

Background. Aging is a major risk factor for a range of chronic diseases. Oxidative stress
theory of aging has been previously proposed as one of the mechanisms responsible for the …

Ageing is a complex process characterised by a systemic and progressive deterioration of
biological functions. As ageing is associated with an increased prevalence of age-related …