Surgical resection rates after neoadjuvant therapy for localized pancreatic ductal adenocarcinoma: meta-analysis

ZJ Brown, V Heh, HE Labiner, GN Brock… - British Journal of …, 2023 - academic.oup.com
Background Neoadjuvant therapy is increasingly being used before surgery for localized
pancreatic cancer. Given the importance of completing multimodal therapy, the aim of this …

Meta-analysis of the impact of neoadjuvant therapy on patterns of recurrence in pancreatic ductal adenocarcinoma

S Schorn, IE Demir, N Samm, F Scheufele… - Bjs Open, 2018 - academic.oup.com
Background Neoadjuvant therapy may increase the rate of radical tumour resection in
patients with pancreatic cancer. Its impact on tumour recurrence has not been investigated …

Survival in locally advanced pancreatic cancer after neoadjuvant therapy and surgical resection

G Gemenetzis, VP Groot, AB Blair, DA Laheru… - Annals of …, 2019 - journals.lww.com
Objective: The aim of the study was to identify the survival of patients with locally advanced
pancreatic cancer (LAPC) and assess the effect of surgical resection after neoadjuvant …

Recurrence patterns for pancreatic ductal adenocarcinoma after upfront resection versus resection following neoadjuvant therapy: a comprehensive meta-analysis

B Ratnayake, AY Savastyuk, M Nayar… - Journal of clinical …, 2020 - mdpi.com
Background: Neoadjuvant therapy (NAT) represents a paradigm shift in the management of
patients with pancreatic ductal adenocarcinoma (PDAC) with perceived benefits including a …

Neoadjuvant therapy for resectable pancreatic cancer: a new standard of care. Pooled data from 3 randomized controlled trials

DL Birrer, H Golcher, R Casadei, SR Haile… - Annals of …, 2021 - journals.lww.com
Objective: The aim of this study was to pool data from randomized controlled trials (RCT)
limited to resectable pancreatic ductal adenocarcinoma (PDAC) to determine whether a …

Primary resection versus neoadjuvant chemoradiation followed by resection for locally resectable or potentially resectable pancreatic carcinoma without distant …

TB Brunner, GG Grabenbauer, T Meyer, H Golcher… - BMC cancer, 2007 - Springer
Background The disappointing results of surgical therapy alone of ductal pancreatic cancer
can only be improved using multimodal approaches. In contrast to adjuvant therapy …

Survival benefit of neoadjuvant therapy in patients with non‐metastatic pancreatic ductal adenocarcinoma: a propensity matching and intention‐to‐treat analysis

M Sugimoto, N Takahashi, MB Farnell… - Journal of surgical …, 2019 - Wiley Online Library
Abstract Background and Objectives Conclusive evidence in favor of neoadjuvant therapy
for those with non‐metastatic pancreatic ductal adenocarcinoma (PDAC) is still lacking. The …

Impact of neoadjuvant therapy in resected pancreatic ductal adenocarcinoma of the pancreatic body or tail on surgical and oncological outcome: a propensity-score …

S Lof, M Korrel, J van Hilst, A Alseidi, G Balzano… - Annals of Surgical …, 2020 - Springer
Background Several studies have suggested a survival benefit of neoadjuvant therapy
(NAT) for pancreatic ductal adenocarcinoma (PDAC) in the pancreatic head. Data …

Neoadjuvant therapy for pancreatic cancer

C Springfeld, CR Ferrone, MHG Katz… - Nature Reviews …, 2023 - nature.com
Patients with localized pancreatic ductal adenocarcinoma (PDAC) are best treated with
surgical resection of the primary tumour and systemic chemotherapy, which provides …

Surgery for pancreatic cancer after neoadjuvant treatment

T Hackert - Annals of gastroenterological surgery, 2018 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) remains to be a therapeutic challenge as only
15%‐20% of all patients present with resectable tumor stages by the time of diagnosis. In the …