The effect of low-magnitude, high-frequency vibration on poly (ethylene glycol)-microencapsulated mesenchymal stem cells

S Mehta, B McClarren, A Aijaz… - Journal of tissue …, 2018 - journals.sagepub.com
Low-magnitude, high-frequency vibration has stimulated osteogenesis in mesenchymal
stem cells when these cells were cultured in certain types of three-dimensional …

[HTML][HTML] Cell adhesion and culture medium dependent changes in the high frequency mechanical vibration induced proliferation, osteogenesis, and intracellular …

HT Halonen, TO Ihalainen, L Hyväri, S Miettinen… - Journal of the …, 2020 - Elsevier
High frequency (HF) mechanical vibration appears beneficial for in vitro osteogenesis of
mesenchymal stem cells (MSCs). However, the current mechanobiological understanding of …

[PDF][PDF] Osteogenic differentiation of bone marrow-derived mesenchymal stromal cells on bone-derived scaffolds: effect of microvibration and role of ERK1/2 activation

Y Zhou, X Guan, Z Zhu, S Gao, C Zhang, C Li… - Eur Cell …, 2011 - ecmjournal.org
Although in vivo studies have shown that low-magnitude, high-frequency (LMHF) vibration
(LM:< 1× g; HF: 20-90 Hz) exhibits anabolic effects on skeletal homeostasis, the underlying …

The effect of dual frequency cyclic compression on matrix deposition by osteoblast-like cells grown in 3D scaffolds and on modulation of VEGF variant expression

V Dumas, A Perrier, L Malaval, N Laroche… - Biomaterials, 2009 - Elsevier
As a strategy to optimise osteointegration of biomaterials by inducing proper extracellular
matrix synthesis, and specifically angiogenic growth factor production and storage, we …

Low magnitude high frequency vibrations expedite the osteogenesis of bone marrow stem cells on paper based 3D scaffolds

O Karadas, G Mese, E Ozcivici - Biomedical Engineering Letters, 2020 - Springer
Anabolic effects of low magnitude high frequency (LMHF) vibrations on bone tissue were
consistently shown in the literature in vivo, however in vitro efforts to elucidate underlying …

Vibration induced osteogenic commitment of mesenchymal stem cells is enhanced by cytoskeletal remodeling but not fluid shear

G Uzer, S Pongkitwitoon, ME Chan, S Judex - Journal of biomechanics, 2013 - Elsevier
Consistent across studies in humans, animals and cells, the application of vibrations can be
anabolic and/or anti-catabolic to bone. The physical mechanisms modulating the vibration …

Effect of low‐magnitude, high‐frequency vibration on osteogenic differentiation of rat mesenchymal stromal cells

E Lau, WD Lee, J Li, A Xiao, JE Davies… - Journal of …, 2011 - Wiley Online Library
Whole body vibration (WBV), consisting of a low‐magnitude, high‐frequency (LMHF) signal,
is anabolic to bone in vivo and may act through alteration of the lineage commitment of …

Low-intensity vibrations normalize adipogenesis-induced morphological and molecular changes of adult mesenchymal stem cells

O Baskan, G Mese, E Ozcivici - Proceedings of the Institution …, 2017 - journals.sagepub.com
Bone marrow mesenchymal stem cells that are committed to adipogenesis were exposed
daily to high-frequency low-intensity mechanical vibrations to understand molecular …

Efficacy of mechanical vibration in regulating mesenchymal stem cells gene expression

AS Safavi, G Rouhi, N Haghighipour, F Bagheri… - In Vitro Cellular & …, 2019 - Springer
This study aimed at investigating the expression of osteoblast and chondrocyte-related
genes in mesenchymal stem cells (MSCs), derived from rabbit adipose tissue, under …

The differentiation of human adipose-derived stem cells (hASCs) into osteoblasts is promoted by low amplitude, high frequency vibration treatment

D Pre, G Ceccarelli, G Gastaldi, A Asti, E Saino, L Visai… - Bone, 2011 - Elsevier
Several studies have demonstrated that tissue culture conditions influence the differentiation
of human adipose-derived stem cells (hASCs). Recently, studies performed on SAOS-2 and …