The host-microbiota relationship has evolved to shape mammalian physiology, including
immunity, metabolism, and development. Germ-free models are widely used to study …

Summary paragraph The host-microbiota relationship has evolved to shape mammalian
processes, including immunity, metabolism, and development–. Host phenotypes change in …

The commensal microbiota impacts specific immune cell populations and their functions at
peripheral sites, such as gut mucosal tissues. However, it remains unknown whether gut …

During colonization of germfree mice with the total fecal microbial community of their
conventionally born and raised siblings (conventionalization), the intestinal mucosal …

Microbial exposure following birth profoundly impacts mammalian immune system
development. Microbiota alterations are associated with increased incidence of allergic and …

The use of isogenic mice is now part of our research culture, not least because major
histocompatibility complex polymorphism is a major roadblock for many experiments in …

The bodies of mammals are hosts to vast microbial communities composed of trillions of
bacteria from thousands of species, whose effects on health and development have begun …

Mammalian pregnancy is characterized by a well-known suite of physiological changes that
support fetal growth and development, thereby positively affecting both maternal and …

Newborns are colonized by maternal microbiota that is essential for offspring health and
development. The composition of these pioneer communities exhibits individual differences …

The microbiome greatly affects health and wellbeing. Evolutionarily, it is doubtful that a host
would rely on chance alone to pass on microbial colonization to its offspring. However, the …