Expression of aldehyde dehydrogenase 3A1 (ALDH3A1) in certain normal and tumor cells is
associated with protection against the growth inhibitory effect of reactive aldehydes …

Aldehyde dehydrogenases (ALDHs) oxidize aldehydes to the corresponding carboxylic
acids using either NAD or NADP as a coenzyme. Aldehydes are highly reactive aliphatic or …

Context: The metabolic function of peroxisome proliferator-activated receptor gamma
(PPARγ) in lung cancer remains unclear. Objectives: To determine the relationship of …

Reactive lipid aldehydes are implicated in the pathogenesis of various oxidative stress-
mediated diseases, including non-alcoholic steatohepatitis, atherosclerosis, Alzheimer's and …

Aldehyde dehydrogenases (ALDHs) are a superfamily of several isoenzymes widely
expressed in bacteria, yeast, plant and animals. Three major classes of ALDHs have been …

Toxic medium chain length alkanals, alkenals, and 4-hydroxyalkenals that are generated
during lipid peroxidation are potential substrates for aldehyde dehydrogenase (ALDH) …

Aldehyde dehydrogenases (ALDHs) are a family of several isoenzymes expressed in
various tissues and in all subcellular fractions. In some tumours, there is an increase of …

Aldehyde dehydrogenase (ALDH) enzymes are critical in the detoxification of aldehydes.
The human genome contains 19 ALDH genes, mutations in which are the basis of several …

Evidence suggests that aldehydic molecules generated during lipid peroxidation (LPO) are
causally involved in most pathophysiological processes associated with oxidative stress. 4 …

In normal liver aldehyde dehydrogenase 3 (ALDH3) is poorly expressed. In hepatoma cells,
its expression increases in direct correlation with the degree of deviation and increased …