Here, we present a major advance of the OrthoFinder method. This extends OrthoFinder's
high accuracy orthogroup inference to provide phylogenetic inference of orthologs, rooted …

Ortholog inference has fundamental importance across the biological sciences,
underpinning phylogenetics, comparative genomics and prediction of gene function. We …

Accurate genome-wide identification of orthologs is a central problem in comparative
genomics, a fact reflected by the numerous orthology identification projects developed in …

Identifying homology relationships between sequences is fundamental to biological
research. Here we provide a novel orthogroup inference algorithm called OrthoFinder that …

Achieving high accuracy in orthology inference is essential for many comparative,
evolutionary and functional genomic analyses, yet the true evolutionary history of genes is …

Background OMA is a project that aims to identify orthologs within publicly available,
complete genomes. With 657 genomes analyzed to date, OMA is one of the largest projects …

Motivation Accurate orthology inference is a fundamental step in many phylogenetics and
comparative analysis. Many methods have been proposed, including OMA (Orthologous …

Motivation: Orthologous proteins in different species are likely to have similar biochemical
function and biological role. When annotating a newly sequenced genome by …

Background Orthologs (genes that have diverged after a speciation event) tend to have
similar function, and so their prediction has become an important component of comparative …

Ortholog detection is essential in functional annotation of genomes, with applications to
phylogenetic tree construction, prediction of protein–protein interaction and other …