The escalation of bacterial resistance to conventional medical antibiotics is a serious
concern worldwide. Improvements to current therapies are urgently needed to address this …

Currently available antibiotics have been effective in treating infectious diseases; however,
the development of resistance to these drugs has led to the emergence of new and the re …

Antimicrobial resistance threatens a resurgence of life-threatening bacterial infections and
the potential demise of many aspects of modern medicine. Despite intensive drug discovery …

New drug development strategies are needed to combat antimicrobial resistance. The object
of this perspective is to highlight one such strategy: treating infections with sets of drugs …

Bacterial infection remains one of the leading causes of death worldwide, and the options for
treating such infections are decreasing, due the rise of antibiotic-resistant bacteria. The …

With multidrug resistant bacteria on the rise, new antibiotic approaches are required.
Although a number of new small molecule antibiotics are currently in the development …

Antibiotic resistance has become one of the major, deadly threats to public health
worldwide. This paper highlights several recent works, which may initiate the development …

Antibiotic resistance continues to evolve and spread beyond all boundaries, resulting in an
increase in morbidity and mortality for non-curable infectious diseases. Due to the failure of …

BACKGROUND Antibiotics are among the most important tools in medicine, but their efficacy
is threatened by the evolution of resistance. Since the earliest days of antibiotics, resistance …

Multidrug-resistant (MDR) organisms constitute a major global health crisis with
antimicrobial resistance (AMR) being among the top ten global public health threats faced …