Key ingredients in Verbena officinalis and determination of their anti-atherosclerotic effect using a computer-aided drug design approach

Y Chen, Y Gan, J Yu, X Ye, W Yu - Frontiers in Plant Science, 2023 - frontiersin.org
Lipid metabolism disorders may considerably contribute to the formation and development
of atherosclerosis (AS). Traditional Chinese medicine has received considerable attention in …

Study on mechanism of Salvia miltiorrhiza treating cardiovascular disease through auxiliary mechanism elucidation system for Chinese medicine

SB He, BX Zhang, HH Wang, Y Wang… - Zhongguo Zhong yao za …, 2015 - europepmc.org
Salvia miltiorrhiza is a traditional Chinese medicine (TCM) and is widely used as a clinically
medication for its efficiency in treating cardiovascular disease. Due to TCM is a …

In Silico Analysis of Anti-Inflammatory and Antioxidant Properties of Bioactive Compounds from Crescentia cujete L.

AL Gonzales, SKH Huang, UTA Sevilla, CY Hsieh… - Molecules, 2023 - mdpi.com
Crescentia cujete is widely known as a medical plant with broad indigenous ethnomedicinal
uses, including anti-inflammatory, and antioxidant. Despite being used for remedies and …

[HTML][HTML] Molecular docking and interactions of pueraria tuberosa with vascular endothelial growth factor receptors

S Asthana, T Agarwal, S Singothu… - Indian Journal of …, 2015 - ncbi.nlm.nih.gov
Pueraria tuberosa is known for its therapeutic potentials in cardiovascular disorders, but its
effect in angiogenesis has not been studied so far. In this study, a computational approach …

Network pharmacology-based strategy combined with molecular docking and in vitro validation study to explore the underlying mechanism of Huo Luo Xiao Ling Dan …

T Sun, W Quan, S Peng, D Yang, J Liu… - Drug Design …, 2023 - Taylor & Francis
Background Huo Luo Xiao Ling Dan (HLXLD), a famous Traditional Chinese Medicine
(TCM) classical formula, possesses anti-atherosclerosis (AS) activity. However, the …

System bioinformatic approach through molecular docking, network pharmacology and microarray data analysis to determine the molecular mechanism underlying …

X Zhang, D Wang, X Ren, AG Atanasov… - Current Protein and …, 2019 - ingentaconnect.com
Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide. Rehmanniae
Radix Praeparata (RRP) is a popular medicinal herb widely used in traditional Chinese …

Target network differences between western drugs and Chinese herbal ingredients in treating cardiovascular disease

P Fu, L Yang, Y Sun, L Ye, Z Cao, K Tang - BMC bioinformatics, 2014 - Springer
Background Western drugs have achieved great successes in CVDs treatment. However,
they may lead to some side effects and drug resistance. On the other hand, more and more …

Network pharmacology-based prediction of the active ingredients and potential targets of Chinese herbal Radix Curcumae formula for application to cardiovascular …

W Tao, X Xu, X Wang, B Li, Y Wang, Y Li… - Journal of …, 2013 - Elsevier
ETHNOPHARMACOLOGY RELEVANCE: Cardiovascular and cerebrovascular diseases
(CCVD), an abnormal function of the heart, brain or blood vessels, are the biggest cause of …

Antihyperlipidemic mechanisms of a formula containing Curcuma xanthorrhiza, Sechium edule, and Syzigium polyanthum: In silico and in vitro studies

F Sangande, K Agustini, K Budipramana - Computational Biology and …, 2023 - Elsevier
Herbal medicines are multi-component and can exhibit synergistic effects in the treatment of
diseases. Sechium edule, Syzigium polyanthum, and Curcuma xanthorrhiza have been …

[HTML][HTML] Network pharmacology based virtual screening of Flavonoids from Dodonea angustifolia and the molecular mechanism against inflammation

MA Alamri, MT ul Qamar - Saudi Pharmaceutical Journal, 2023 - Elsevier
Inflammation is a nonspecific immune response against injury caused by a harmful agent
that strives to restore tissue function and homeostasis. Dodonaea angustifolia Lf …