NIRS measures in pain and analgesia: fundamentals, features, and function

KD Karunakaran, K Peng, D Berry, S Green… - Neuroscience & …, 2021 - Elsevier
Current pain assessment techniques based only on clinical evaluation and self-reports are
not objective and may lead to inadequate treatment. Having a functional biomarker will add …

Using prerecorded hemodynamic response functions in detecting prefrontal pain response: a functional near-infrared spectroscopy study

K Peng, MA Yücel, CM Aasted, SC Steele… - …, 2018 - spiedigitallibrary.org
Currently, there is no method for providing a nonverbal objective assessment of pain.
Recent work using functional near-infrared spectroscopy (fNIRS) has revealed its potential …

Morphine attenuates fNIRS signal associated with painful stimuli in the medial frontopolar cortex (medial BA 10)

K Peng, MA Yücel, SC Steele, EA Bittner… - Frontiers in Human …, 2018 - frontiersin.org
Functional near infrared spectroscopy (fNIRS) is a non-invasive optical imaging method that
provides continuous measure of cortical brain functions. One application has been its use in …

Toward a functional near-infrared spectroscopy-based monitoring of pain assessment for nonverbal patients

R Fernandez Rojas, X Huang… - Journal of biomedical …, 2017 - spiedigitallibrary.org
Pain diagnosis for nonverbal patients represents a challenge in clinical settings.
Neuroimaging methods, such as functional magnetic resonance imaging and functional …

Frontal lobe hemodynamic responses to painful stimulation: a potential brain marker of nociception

CM Aasted, MA Yücel, SC Steele, K Peng, DA Boas… - PLoS …, 2016 - journals.plos.org
The purpose of this study was to use functional near-infrared spectroscopy (fNIRS) to
examine patterns of both activation and deactivation that occur in the frontal lobe in …

Specificity of hemodynamic brain responses to painful stimuli: a functional near-infrared spectroscopy study

MA Yücel, CM Aasted, MP Petkov, D Borsook… - Scientific reports, 2015 - nature.com
Assessing pain in individuals not able to communicate (eg infants, under surgery, or
following stroke) is difficult due to the lack of non-verbal objective measures of pain. Near …

Functional near-infrared spectroscopy study on tonic pain activation by cold pressor test

Z Barati, I Zakeri, K Pourrezaei - Neurophotonics, 2017 - spiedigitallibrary.org
Functional near-infrared spectroscopy (fNIRS) has recently been suggested for monitoring
cortical hemodynamic response to experimental and clinical acute pain. However, the …

Physiological effects of mechanical pain stimulation at the lower back measured by functional near-infrared spectroscopy and capnography

L Holper, A Gross, F Scholkmann… - Journal of integrative …, 2014 - World Scientific
The aim was to investigate the effect of mechanical pain stimulation at the lower back on
hemodynamic and oxygenation changes in the prefrontal cortex (PFC) assessed by …

A machine learning approach for the identification of a biomarker of human pain using fNIRS

R Fernandez Rojas, X Huang, KL Ou - Scientific reports, 2019 - nature.com
Pain is a highly unpleasant sensory and emotional experience, and no objective diagnosis
test exists to assess it. In clinical practice there are two main methods for the estimation of …

Application of functional data analysis in classification and clustering of functional near-infrared spectroscopy signal in response to noxious stimuli

A Pourshoghi, I Zakeri… - Journal of Biomedical …, 2016 - spiedigitallibrary.org
We introduce the application of functional data analysis (fDA) on functional near-infrared
spectroscopy (fNIRS) signals for the development of an accurate and clinically practical …