A deep-learning approach to predict bleeding risk over time in patients on extended anticoagulation therapy

SS Fard, TJ Perkins, PS Wells - Journal of Thrombosis and Haemostasis, 2024 - Elsevier
Background Thus far, all the clinical models developed to predict major bleeding in patients
on extended anticoagulation therapy use the baseline predictors to stratify patients into …

[HTML][HTML] Application of artificial neural network in daily prediction of bleeding in ICU patients treated with anti-thrombotic therapy

D Chen, R Wang, Y Jiang, Z Xing, Q Sheng… - BMC Medical Informatics …, 2023 - Springer
Objectives Anti-thrombotic therapy is the basis of thrombosis prevention and treatment.
Bleeding is the main adverse event of anti-thrombosis. Existing laboratory indicators cannot …

[HTML][HTML] Prediction of bleeding risk in patients on extended oral anticoagulation for venous thromboembolism

PS Wells, MJ Kovacs, D Anderson, SR Kahn, C Kearon… - Blood, 2016 - Elsevier
Background: While tools exist to predict the risk of major bleeding in patients on oral
anticoagulation therapy (OAT) for venous thromboembolism (VTE), these have focused on …

Machine Learning-Based Bleeding Risk Predictions in Atrial Fibrillation Patients on Direct Oral Anticoagulants

R Chaudhary, M Nourelahi, F Thoma, WF Gellad… - medRxiv, 2024 - medrxiv.org
Importance: Accurately predicting major bleeding events in non-valvular atrial fibrillation
(AF) patients on direct oral anticoagulants (DOACs) is crucial for personalized treatment and …

[HTML][HTML] Machine learning analysis of bleeding status in venous thromboembolism patients

SS Fard, TJ Perkins, PS Wells - Research and Practice in Thrombosis and …, 2024 - Elsevier
Background Anticoagulation therapy is the mainstay of therapy for patients with venous
thromboembolism (VTE). However, continuing or stopping anticoagulants after the first 3 to 6 …

[HTML][HTML] Predictive ability of scores for bleeding risk in heart disease outpatients on warfarin in Brazil

JAQ Oliveira, AL Pinho Ribeiro, DD Ribeiro, V Nobre… - PLoS …, 2018 - journals.plos.org
Introduction Bleeding is a common complication in patients taking warfarin. We sought to
compare the performance of nine prediction models for bleeding risk in warfarin-treated …

Using machine learning to predict the bleeding risk for patients with cardiac valve replacement treated with warfarin in hospitalized

Y Hu, X Zhang, M Wei, T Yang, J Chen… - … and Drug Safety, 2024 - Wiley Online Library
Background Distinguishing warfarin‐related bleeding risk at the bedside remains
challenging. Studies indicate that warfarin therapy should be suspended when international …

Novel bleeding prediction model in atrial fibrillation patients on new oral anticoagulants

O Barnett-Griness, N Stein, A Kotler, W Saliba… - Heart, 2022 - heart.bmj.com
Objective Clinical models such as the HAS-BLED (standing for Hypertension, Abnormal
liver/renal function, Stroke history, Bleeding history or predisposition, Labile INR, Elderly …

Machine learning to predict major bleeding during anticoagulation for venous thromboembolism: possibilities and limitations

D Mora, J Mateo, JA Nieto, B Bikdeli… - British Journal of …, 2023 - Wiley Online Library
Predictive tools for major bleeding (MB) using machine learning (ML) might be
advantageous over traditional methods. We used data from the Registro Informatizado de …

Predicting major bleeding during extended anticoagulation for unprovoked or weakly provoked venous thromboembolism

PS Wells, T Tritschler, F Khan, DR Anderson… - Blood …, 2022 - ashpublications.org
No clinical prediction model has been specifically developed or validated to identify patients
with unprovoked venous thromboembolism (VTE) who are at high risk of major bleeding …