Drug resistance in malaria-in a nutshell

D Bhattacharjee, G Shivaprakash - Journal of Applied …, 2016 - japsonline.com
One peek into the history of malaria, shows us that despite many attempts by mankind to
counter the development and propagation of malaria, it has always risen back like a …

[HTML][HTML] Drug targets for resistant malaria: historic to future perspectives

S Kumar, TR Bhardwaj, DN Prasad… - Biomedicine & …, 2018 - Elsevier
New antimalarial targets are the prime need for the discovery of potent drug candidates. In
order to fulfill this objective, antimalarial drug researches are focusing on promising targets …

Mechanisms of drug resistance in malaria: current and new challenges

P Cravo, R Culleton, A Afonso… - Anti-Infective Agents …, 2006 - ingentaconnect.com
Anti-malarial chemotherapy based on a limited number of drugs has been the mainstay of
malaria control for many decades. However, the lack of new effective and affordable drugs …

Drug‐resistant malaria− an insight

JE Hyde - The FEBS journal, 2007 - Wiley Online Library
Despite intensive research extending back to the 1930s, when the first synthetic antimalarial
drugs made their appearance, the repertoire of clinically licensed formulations remains very …

Drug resistance in malaria

SC Parija, I Praharaj - Indian Journal of Medical Microbiology, 2011 - Elsevier
Antimalarial chemotherapy is an important component of all malaria control programmes
throughout the world. This is especially so in light of the fact that there are no antimalarial …

An overview of available antimalarials: discovery, mode of action and drug resistance

YQ Tang, Q Ye, H Huang… - Current Molecular …, 2020 - ingentaconnect.com
Malaria is one of the three most deadly infectious diseases in the world and seriously
endangers human health and life. To reduce the public health burden of this disease …

Plasmodium falciparum: Multidrug resistance

S Rout, RK Mahapatra - Chemical biology & drug design, 2019 - Wiley Online Library
Malaria is the most lethal and debilitating disease caused by the protozoan parasite
Plasmodium worldwide. The most severe forms of disease and the incidence rates of …

Resisting resistance: is there a solution for malaria?

BK Verlinden, A Louw, LM Birkholtz - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Currently, widely used antimalarial drugs have a limited clinical lifespan due to
parasite resistance development. With resistance continuously rising, antimalarial drug …

Molecular targets for malarial chemotherapy: a review

DK Yadav, S Kumar, MK Teli, R Yadav… - Current topics in …, 2019 - ingentaconnect.com
The malaria parasite resistance to the existing drugs is a serious problem to the currently
used antimalarials and, thus, highlights the urgent need to develop new and effective anti …

The mechanisms of drug action and resistance in malaria

AF Cowman - Molecular genetics of drug resistance. Amsterdam …, 1997 - books.google.com
Malaria has plagued man throughout recorded history and results in the death of over two
million people per year and increased morbidity. The importance of malaria in human history …