New antimalarial targets are the prime need for the discovery of potent drug candidates. In order to fulfill this objective, antimalarial drug researches are focusing on promising targets …
Anti-malarial chemotherapy based on a limited number of drugs has been the mainstay of malaria control for many decades. However, the lack of new effective and affordable drugs …
JE Hyde - The FEBS journal, 2007 - Wiley Online Library
Despite intensive research extending back to the 1930s, when the first synthetic antimalarial drugs made their appearance, the repertoire of clinically licensed formulations remains very …
SC Parija, I Praharaj - Indian Journal of Medical Microbiology, 2011 - Elsevier
Antimalarial chemotherapy is an important component of all malaria control programmes throughout the world. This is especially so in light of the fact that there are no antimalarial …
YQ Tang, Q Ye, H Huang… - Current Molecular …, 2020 - ingentaconnect.com
Malaria is one of the three most deadly infectious diseases in the world and seriously endangers human health and life. To reduce the public health burden of this disease …
S Rout, RK Mahapatra - Chemical biology & drug design, 2019 - Wiley Online Library
Malaria is the most lethal and debilitating disease caused by the protozoan parasite Plasmodium worldwide. The most severe forms of disease and the incidence rates of …
BK Verlinden, A Louw, LM Birkholtz - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Currently, widely used antimalarial drugs have a limited clinical lifespan due to parasite resistance development. With resistance continuously rising, antimalarial drug …
The malaria parasite resistance to the existing drugs is a serious problem to the currently used antimalarials and, thus, highlights the urgent need to develop new and effective anti …
AF Cowman - Molecular genetics of drug resistance. Amsterdam …, 1997 - books.google.com
Malaria has plagued man throughout recorded history and results in the death of over two million people per year and increased morbidity. The importance of malaria in human history …