Neuroimaging-based brain age estimation: A promising personalized biomarker in neuropsychiatry

D Sone, I Beheshti - Journal of Personalized Medicine, 2022 - mdpi.com
It is now possible to estimate an individual's brain age via brain scans and machine-learning
models. This validated technique has opened up new avenues for addressing clinical …

Machine learning for brain age prediction: Introduction to methods and clinical applications

L Baecker, R Garcia-Dias, S Vieira, C Scarpazza… - …, 2021 - thelancet.com
The rise of machine learning has unlocked new ways of analysing structural neuroimaging
data, including brain age prediction. In this state-of-the-art review, we provide an …

Investigating systematic bias in brain age estimation with application to post‐traumatic stress disorders

H Liang, F Zhang, X Niu - 2019 - Wiley Online Library
Brain age prediction using machine‐learning techniques has recently attracted growing
attention, as it has the potential to serve as a biomarker for characterizing the typical brain …

A review of neuroimaging-driven brain age estimation for identification of brain disorders and health conditions

S Mishra, I Beheshti, P Khanna - IEEE Reviews in Biomedical …, 2021 - ieeexplore.ieee.org
Background: Neuroimage analysis has made it possible to perform various anatomical
analyses of the brain regions and helps detect different brain conditions/disorders. Recently …

Estimating brain age based on a uniform healthy population with deep learning and structural magnetic resonance imaging

X Feng, ZC Lipton, J Yang, SA Small… - Neurobiology of …, 2020 - Elsevier
Numerous studies have established that estimated brain age constitutes a valuable
biomarker that is predictive of cognitive decline and various neurological diseases. In this …

Improved prediction of brain age using multimodal neuroimaging data

X Niu, F Zhang, J Kounios, H Liang - Human brain mapping, 2020 - Wiley Online Library
Brain age prediction based on imaging data and machine learning (ML) methods has great
potential to provide insights into the development of cognition and mental disorders. Though …

Brain-age prediction: A systematic comparison of machine learning workflows

S More, G Antonopoulos, F Hoffstaedter, J Caspers… - NeuroImage, 2023 - Elsevier
The difference between age predicted using anatomical brain scans and chronological age,
ie, the brain-age delta, provides a proxy for atypical aging. Various data representations and …

Ten Years of BrainAGE as a Neuroimaging Biomarker of Brain Aging: What Insights Have We Gained?

K Franke, C Gaser - Frontiers in neurology, 2019 - frontiersin.org
With the aging population, prevalence of neurodegenerative diseases is increasing, thus
placing a growing burden on individuals and the whole society. However, individual rates of …

Predicting brain age at slice level: convolutional neural networks and consequences for interpretability

PL Ballester, LT Da Silva, M Marcon, NB Esper… - Frontiers in …, 2021 - frontiersin.org
Problem: Chronological aging in later life is associated with brain degeneration processes
and increased risk for disease such as stroke and dementia. With a worldwide tendency of …

Probing multiple algorithms to calculate brain age: Examining reliability, relations with demographics, and predictive power

E Bacas, I Kahhalé, PR Raamana… - Human Brain …, 2023 - Wiley Online Library
The calculation of so‐called “brain age” from structural MRIs has been an emerging
biomarker in aging research. Data suggests that discrepancies between chronological age …