According to birth certificates, the life of a child begins once their body comes out of the
mother's womb. But when does their organismal life begin? Science holds a palette of …

Arking (2006) proposed a general model of the human life span that is useful to structure this
review. He divided the human life span into three phases: the development, the health, and …

There is consensus among biogerontologists that aging occurs either as the result of a
purposeful genome-based, evolved program or due to spontaneous, randomly occurring …

Are diseases caused by aging? What are the mechanisms of aging? Do all species age?
These hotly debated questions revolve around a unitary definition of aging. Because we use …

Traditionally, gerontological research is focused on later stages of life cycle. Accumulating
evidence, however, indicates that the rate of aging-associated functional decline …

In recent decades, the study of biological aging has evolved from simplistic theories like the
free radical theory to more complex and nuanced perspectives. In particular, the …

At a recent symposium on aging biology, a debate was held as to whether or not we know
what biological aging is. Most of the participants were struck not only by the lack of …

The current understanding of the biology of aging is largely based on research aimed at
identifying factors that influence lifespan. However, lifespan as a sole proxy measure of …

The biological mechanism by which aging occurs remains one of the great unsolved
problems of biology. In the face of the spectacular explosion of basic knowledge and …

As a nod to the oft-quoted evolutionary theorist George Williams,“It is remarkable that after a
seemingly miraculous feat of morphogenesis, a complex metazoan should be unable to …