As is apparent from the many contributions to this Special Issue of the Journal, the impact of
age on immunity is nefarious, with all manner of dysregulated responses attributed to …

Immunosenescence resulting in decreased ability to control infectious disease contributes to
morbidity and mortality not only in the very elderly, but in all likelihood already from middle …

Immunosenescence contributes materially to the decreased ability of the elderly to control
infectious disease, which is also reflected in their generally poor response to vaccination …

It has been apparent for some time that profound and complex changes in the immune
response occur as species including mouse and man undergo post-maturational aging …

Accumulating data are documenting an inverse relationship between immune status,
response to vaccination, health, and longevity, suggesting that the immune system becomes …

Human immunosenescence contributes to morbidity and mortality in later life. The age-
associated increasing incidence ofcancer and cardiovascular disease plateaus at around 80 …

Centenarians are the best example of successful ageing, since they have escaped the major
age-associated diseases, alzd most are in good mental and physical condition. Heye …

Immunosenescence is an age-associated decline of immunity involving multiorgan changes.
As the mean age of the population increases, an increase of diverse pathologies associated …

Understanding why we age and how that process can be delayed or reversed are topics that
have engaged both researchers and the general public [1]. From a scientific perspective …

In the classic sense, immunity is the ability of an organism to resist disease. On the one
hand, we must distinguish between age and disease; on the other hand, the interaction …