Associação entre variantes nos genes TNF, IL6 e IL1B e gravidade da Covid-19
MF Feira - 2022 - lume.ufrgs.br
Covid-19 (coronavirus disease 2019) is an infectious disease caused by the Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is transmitted especially through direct …
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is transmitted especially through direct …
[HTML][HTML] Investigação das correlações dos polimorfismos dos genes da IL-6, TNF, IL-1Β, IL-10, e IL-17A com a gravidade e desfecho clínico da Covid-19
OB Domingues - 2024 - repositorio.ufc.br
The SARS-CoV-2, which caused the COVID-19 pandemic, is a virus that primarily affects the
respiratory system, with evidence of tropism for other organs. The manifestations of the …
respiratory system, with evidence of tropism for other organs. The manifestations of the …
Association between polymorphisms in TLR3, TICAM1 and IFNA1 genes and covid-19 severity in Southern Brazil
M Braga, MAS Shiga, PES Silva… - Expert Review of …, 2024 - Taylor & Francis
Background A distinct phenotype in Coronavirus disease 2019 (Covid-19) was observed in
severe patients, consisting of a highly impaired interferon (IFN) type I response, an …
severe patients, consisting of a highly impaired interferon (IFN) type I response, an …
Modifying effects of TNF-α, IL-6 and VDR genes on the development risk and the course of COVID-19. Pilot study
L Fishchuk, Z Rossokha, V Pokhylko… - Drug Metabolism and …, 2022 - degruyter.com
Objectives COVID-19 continues to range around the world and set morbidity and mortality
antirecords. Determining the role of genetic factors in the development of COVID-19 may …
antirecords. Determining the role of genetic factors in the development of COVID-19 may …
Single nucleotide polymorphisms located in TNFA, IL1RN, IL6R, and IL6 genes are associated with COVID‐19 risk and severity in an Iranian population
M Rokni, M Sarhadi, M Heidari Nia… - Cell Biology …, 2022 - Wiley Online Library
Cytokines play pivotal functions in coronavirus disease 2019 (COVID‐19) pathogenesis.
However, little is known about the rationale and importance of genetic variations associated …
However, little is known about the rationale and importance of genetic variations associated …
Association of polymorphisms of IL-6 pathway genes (IL6, IL6R and IL6ST) with COVID-19 severity in an Amazonian population
FBB Rodrigues, R da Silva, EF Santos, MTFM de Brito… - Viruses, 2023 - mdpi.com
Interleukin-6 has been recognized as a major role player in COVID-19 severity, being an
important regulator of the cytokine storm. Hence, the evaluation of the influence of …
important regulator of the cytokine storm. Hence, the evaluation of the influence of …
Understanding the impact of cytokine gene polymorphisms (IL10 rs1800872 and TNF rs1800629) on COVID-19 severity: A comprehensive meta-analysis
S Velmurugan, R Pauline, L Kulanthaivel, GK Subbaraj - Human Gene, 2024 - Elsevier
Aim The anti-inflammatory and pro-inflammatory cytokine genes are linked to the severity
and prognosis of individuals with respiratory and non-respiratory viral infections. The …
and prognosis of individuals with respiratory and non-respiratory viral infections. The …
Role of Interleukin-6 and Tumor Necrosis Factor-Alpha Genes Polymorphisms in COVID-19 Progression
EM Ghoneim, A Abd El Raouf Khalil… - Egyptian Journal of …, 2024 - ejmm.journals.ekb.eg
Background: IL6 and tumor necrosis factor-ɑ (TNF-ɑ) are important cytokines that determine
the host defense mechanism, that play a pivotal role in COVID-19 progression. Objectives …
the host defense mechanism, that play a pivotal role in COVID-19 progression. Objectives …
Association of the C3953T (rs1143634) variant of the interleukin 1 beta gene with the features of a complicated course of COVID-19-associated pneumonia
V Pokhylko, Y Cherniavska, L Fishchuk… - Molecular Biology …, 2024 - Springer
Background The pro-inflammatory cytokine IL-1 plays an important role in severe COVID-19.
A change in IL-1 production may be associated with a mutation in the IL1Β gene. Our study …
A change in IL-1 production may be associated with a mutation in the IL1Β gene. Our study …
Association of IL-10–592 C> A/-1082 A> G and the TNFα-308 G> A with susceptibility to COVID-19 and clinical outcomes
RE Eldesouki, RM Kishk, NM Abd El-Fadeal… - BMC medical …, 2024 - Springer
Background Variation in host immune responses to SARS-CoV-2 is regulated by multiple
genes involved in innate viral response and cytokine storm emergence like IL-10 and TNFa …
genes involved in innate viral response and cytokine storm emergence like IL-10 and TNFa …