Historically, studies on the neural basis of fear conditioning have emphasized the role of the
central nervous system. However, there is growing evidence for the role of the autonomic …

Classical Pavlovian fear conditioning remains the most widely employed experimental
model of fear and anxiety, and continues to inform contemporary pathophysiological …

To explore the ventral medial prefrontal cortex (vMPFC) involvement in behavioral and
autonomic fear-conditioned responses to context, vMPFC synaptic transmission was …

Understanding transient dynamics of the autonomic nervous system during fear learning
remains a critical step to translate basic research into treatment of fear‐related disorders. In …

Both clinicians and neuroscientists have been long interested in the topic of fear
conditioning, with recent advances in neuroscience, in particular, igniting a shared interest …

experiment with “Little Albert.” In this experiment, Albert, a normal and healthy child
attending day care, was shown a white rat by Rayner. Not surprisingly, Albert's first reaction …

In the whole animal kingdom, fear learning is an essential process that allows living beings
to survive. Therefore, revealing the neurophysiological processes that govern the …

In the last century, the paradigm of fear conditioning has greatly evolved in a variety of
scientific fields. The techniques, protocols, and analysis methods now most used have …

Current models of human fear learning processes emphasize a primary contribution of the
ventromedial prefrontal cortex (vmPFC) to fear inhibition (ie, fear extinction). Here, we …

Fear and anxiety are adaptive responses but if left unregulated, or inappropriately regulated,
they become biologically and socially maladaptive. Dysregulated emotions are manifest in a …