The purpose of this state-of-the-art review is to update the American College of Chest
Physicians 2006 guideline on global physiology and pathophysiology of cough. A review of …

Objective: The anatomy and neurophysiology of cough has been reviewed in the preceding
section. The objective of this section is to describe how the varied anatomic components of …

Cough is usually defined as a three-phase event, although for convenience clinicians may
prefer to define it as only the expiratory expulsive efforts. Cough may occur as a single event …

Cough is a complex physiologic event that protects the lungs from mechanical, chemical,
and thermal injury. It is a normal reflex and therefore helps humans to adapt to an …

Highlights•Cough endpoints include severity, frequency, intensity, urge and quality of
life.•Cough frequency monitoring is emerging as a primary outcome measure for antitussive …

Cough is a primitive reflex typically consisting of an initiating deep inspiration, glottal
closure, and an explosive expiration accompanied by a sound. The flow characteristics of …

Considerable progress has been achieved in the development of tools that assess cough.
The visual analogue scale (VAS) for cough severity is widely used in clinical practice …

Cough is one of a group of defensive respiratory reflexes. The reflex is a complex one, with
the afferent pathway within the vagus nerve, and the efferent pathway within the somatic …

Background and objective: The assessment of chronic cough has been improved by the
development of objective ambulatory cough monitoring systems and subjective quality of life …

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