Gene silencing in adult Popillia japonica through feeding of double‐stranded RNA (dsRNA) complexed with branched amphiphilic peptide capsules (BAPCs)

E Carroll, N Kunte, E McGraw, S Gautam… - Frontiers in Insect …, 2023 - frontiersin.org
Gene silencing by feeding double-stranded (dsRNA) holds promise as a novel pest
management strategy. Nonetheless, degradation of dsRNA in the environment and within …

Insight into Cellular Uptake and Transcytosis of Peptide Nanoparticles in Spodoptera frugiperda Cells and Isolated Midgut

E McGraw, JD Roberts, N Kunte, M Westerfield… - ACS …, 2022 - ACS Publications
Silencing genes in insects by introducing double-stranded RNA (dsRNA) in the diet holds
promise as a new pest management method. It has been demonstrated that nanoparticles …

Delivery of lethal dsRNAs in insect diets by branched amphiphilic peptide capsules

LA Avila, R Chandrasekar, KE Wilkinson… - Journal of controlled …, 2018 - Elsevier
Abstract Development of new and specific insect pest management methods is critical for
overcoming pesticide resistance and collateral off-target killings. Gene silencing by feeding …

The Study of Cell-Penetrating Peptides to Deliver dsRNA and siRNA by Feeding in the Desert Locust, Schistocerca gregaria

E Vogel, D Santos, C Huygens, P Peeters… - Insects, 2023 - mdpi.com
Simple Summary This study focuses on the desert locust, a critical insect pest species for
agriculture. We aimed at investigating how to induce RNA interference by feeding in this …

Delivery of lethal dsRNAs in insect diets by branched amphiphilic peptide capsules

SM Barros, R Chandrasekar… - The FASEB …, 2019 - Wiley Online Library
Branched Amphiphilic Peptides Capsules (BAPCs™) are a novel class of nano‐carriers
constituted from the spontaneous co‐assembly of two unique, engineered peptide …

RNA interference cannot be operated in lepidopteran insect? A nanocarrier breaks bottlenecks at all developmental stages of Spodoptera frugiperda

Z Chao, Z Ma, Y Zhang, S Yan, J Shen - 2022 - researchsquare.com
RNA interference (RNAi) has become an essential technique in functional analysis of insect
genes and pest management. However, insensitivity to RNAi is the main obstacle that limits …

Oral delivery of dsRNA lipoplexes to German cockroach protects dsRNA from degradation and induces RNAi response

YH Lin, JH Huang, Y Liu, X Belles… - Pest management …, 2017 - Wiley Online Library
BACKGROUND In the past years, the concept of RNAi application for insect pest control has
been proposed, considering the disruption of vital genes. However, the efficiency of RNAi is …

Practical use of RNA interference: oral delivery of double-stranded RNA in liposome carriers for cockroaches

JH Huang, Y Liu, YH Lin, X Belles, HJ Lee - JoVE (Journal of Visualized …, 2018 - jove.com
RNA interference (RNAi) has been widely applied for uncovering the biological functions of
numerous genes, and has been envisaged as a pest control tool operating by disruption of …

Establishment of star polycation-based RNA interference system in all developmental stages of fall armyworm Spodoptera frugiperda.

Z Chao, Z Ma, Y Zhang, S Yan… - Entomologia …, 2023 - search.ebscohost.com
RNA interference (RNAi) has become an essential technique in functional analysis of insect
genes and pest management. However, insensitivity to RNAi is the main obstacle that limits …

Protamine–Lipid–dsRNA Nanoparticles Improve RNAi Efficiency in the Fall Armyworm, Spodoptera frugiperda

RK Dhandapani, D Gurusamy… - Journal of Agricultural and …, 2022 - ACS Publications
Developing safe and effective double-stranded RNA (dsRNA) delivery systems remains a
major challenge for gene silencing, especially in lepidopteran insects. This study evaluated …