Host-mediated lung inflammation is present, and drives mortality, in the critical illness
caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with …

Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic
variation influences the development of illness requiring critical care or hospitalization–after …

SARS-CoV-2 infection is benign in most individuals but, in around 10% of cases, it triggers
hypoxaemic COVID-19 pneumonia, which leads to critical illness in around 3% of cases …

The acute clinical manifestations of COVID-19 have been well characterized,, but the post-
acute sequelae of this disease have not been comprehensively described. Here we use the …

The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants jeopardizes the protective antiviral immunity induced after infection or …

Respiratory failure is the leading cause of death in patients with severe SARS-CoV-2
infection,, but the host response at the lung tissue level is poorly understood. Here we …

The genetic make-up of an individual contributes to the susceptibility and response to viral
infection. Although environmental, clinical and social factors have a role in the chance of …

A long-term perspective on immunity to COVID Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Recent studies have provided insights into the pathology of and immune response to COVID-
19–. However, a thorough investigation of the interplay between infected cells and the …

A new coronavirus was recently discovered and named severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). Infection with SARS-CoV-2 in humans causes coronavirus …