The role of oxidative stress in fetal alcohol spectrum disorders

PS Brocardo, J Gil-Mohapel, BR Christie - Brain research reviews, 2011 - Elsevier
The ingestion of alcohol/ethanol during pregnancy can result in abnormal fetal development
in both humans and a variety of experimental animal models. Depending on the pattern of …

Fetal alcohol spectrum disorder: potential role of endocannabinoids signaling

BS Basavarajappa - Brain sciences, 2015 - mdpi.com
One of the unique features of prenatal alcohol exposure in humans is impaired cognitive
and behavioral function resulting from damage to the central nervous system (CNS), which …

[HTML][HTML] Mechanisms of alcohol-induced damage to the developing nervous system

CR Goodlett, KH Horn - Alcohol Research & Health, 2001 - ncbi.nlm.nih.gov
Numerous mechanisms likely contribute to the damaging effects of prenatal alcohol
exposure on the developing fetus and particularly the developing central nervous system …

The effects of ethanol exposure during distinct periods of brain development on oxidative stress in the adult rat brain

PS Brocardo, J Gil‐Mohapel, R Wortman… - Alcoholism: Clinical …, 2017 - Wiley Online Library
Background The consumption of alcohol during pregnancy can result in abnormal fetal
development and impaired brain function in humans and experimental animal models …

Ethanol influences on Bax translocation, mitochondrial membrane potential, and reactive oxygen species generation are modulated by vitamin E and brain‐derived …

MB Heaton, M Paiva… - Alcoholism: Clinical and …, 2011 - Wiley Online Library
Background: This study investigated ethanol influences on intracellular events that
predispose developing neurons toward apoptosis and the capacity of the antioxidant α …

Mechanisms involved in central nervous system dysfunctions induced by prenatal ethanol exposure

C Guerri - Neurotoxicity research, 2002 - Springer
Clinical and experimental evidence has demonstrated that ethanol is a teratogen, and that
its consumption during pregnancy induces harmful effects on the developing foetus that …

Fetal alcohol spectrum disorder: pathogenesis and mechanisms

KK Sulik - Handbook of clinical neurology, 2014 - Elsevier
This chapter provides an overview of animal model-based studies that have generated
information critical to our understanding of the pathogenesis and mechanisms underlying …

Mechanisms underlying neuro-inflammation and neurodevelopmental toxicity in the mouse neocortex following prenatal exposure to ethanol

M Komada, N Hara, S Kawachi, K Kawachi… - Scientific reports, 2017 - nature.com
Fetal alcohol spectrum disorders (FASD) constitute a wide range of disorders that arise from
prenatal exposure to ethanol (EtOH). However, detailed reports regarding the adverse …

Fetal alcohol syndrome: the vulnerability of the developing brain and possible mechanisms of damage

JR West, WJA Chen, NJ Pantazis - Metabolic brain disease, 1994 - Springer
Fetal alcohol exposure has multiple deleterious effects on brain development, and
represents a leading known cause of mental retardation. This review of the effects of alcohol …

Placental hypoxia and foetal development versus alcohol exposure in pregnancy

C Bosco, E Diaz - Alcohol and alcoholism, 2012 - academic.oup.com
Aims: To examine the causes of variability in the effect of maternal drinking on the foetus,
with particular reference to the pattern, frequency and duration of the period of drinking …