Deciphering the DNA methylome in women with PCOS diagnosed using the new international evidence-based guidelines

Y Wang, X Gao, Z Yang, X Yan, X He, T Guo… - Human …, 2023 - academic.oup.com
STUDY QUESTION Is there any methylome alteration in women with PCOS who were
diagnosed using the new international evidence-based guidelines? SUMMARY ANSWER A …

Role of genomic DNA methylation in PCOS pathogenesis: a systematic review and meta-analysis involving case-controlled clinical studies

K Rawat, A Sandhu, V Gautam… - Molecular Human …, 2022 - academic.oup.com
Polycystic ovary syndrome (PCOS) is often associated with aberrant DNA methylation.
Despite the advances in diagnostics and treatment of PCOS, the pathophysiological …

[HTML][HTML] Genome-wide screen of ovary-specific DNA methylation in polycystic ovary syndrome

YY Yu, CX Sun, YK Liu, Y Li, L Wang, W Zhang - Fertility and sterility, 2015 - Elsevier
Objective To compare genome-wide DNA methylation profiles in ovary tissue from women
with polycystic ovary syndrome (PCOS) and healthy controls. Design Case-control study …

[HTML][HTML] Differential DNA methylation patterns of polycystic ovarian syndrome in whole blood of Chinese women

S Li, D Zhu, H Duan, A Ren, D Glintborg, M Andersen… - Oncotarget, 2017 - ncbi.nlm.nih.gov
As a universally common endocrinopathy in women of reproductive age, the polycystic
ovarian syndrome is characterized by composite clinical phenotypes reflecting the …

[HTML][HTML] Genome-wide DNA methylation and gene expression patterns provide insight into polycystic ovary syndrome development

XX Wang, JZ Wei, J Jiao, SY Jiang, DH Yu, D Li - Oncotarget, 2014 - ncbi.nlm.nih.gov
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in
women. However, the epigenetic mechanism involved in PCOS progression remains largely …

3 CpG methylation biomarkers for the diagnosis of polycystic ovary syndrome (PCOS) in blood samples

L Xie, X Jiang, Y Chen, C Huang… - … Chemistry & High …, 2022 - ingentaconnect.com
Background: Polycystic ovary syndrome (PCOS) is a common endocrine disease in women
that seriously interferes with patient's metabolic and reproductive functions. The current …

Study of association of global deoxyribonucleic acid methylation in women with polycystic ovary syndrome

RP Ray, M Padhi, S Jena, R Patnaik… - Journal of Human …, 2022 - journals.lww.com
Background: Polycystic ovary syndrome (PCOS), a common endocrine disorder affecting 5%–
10% of reproductive age women worldwide, associated with various metabolic morbidities …

DNA methylation associated with polycystic ovary syndrome: a systematic review

AG Miranda, MM Seneda, LR Faustino - Archives of Gynecology and …, 2024 - Springer
Purpose Polycystic ovary syndrome (PCOS) is an endocrine metabolic disease that affects
women of reproductive age and is one of the main causes of anovulatory infertility. However …

Integrated analysis of DNA methylation and transcriptome profiling of polycystic ovary syndrome

L Liu, D He, Y Wang, M Sheng - Molecular Medicine …, 2020 - spandidos-publications.com
The present study aimed to identify potentially important biomarkers associated with
polycystic ovary syndrome (PCOS) by integrating DNA methylation with transcriptome …

Analysis of methylome, transcriptome, and lipid metabolites to understand the molecular abnormalities in polycystic ovary syndrome

F Zhang, Y Ding, B Zhang, M He, Z Wang… - Diabetes, Metabolic …, 2023 - Taylor & Francis
Purpose This study aimed to identify differentially methylated genes (DMGs) and
differentially expressed genes (DEGs) to investigate new biomarkers for the diagnosis and …