[HTML][HTML] SARS-CoV-2 receptors are expressed on human platelets and the effect of aspirin on clinical outcomes in COVID-19 patients

A Sahai, R Bhandari, M Koupenova… - Research …, 2020 - ncbi.nlm.nih.gov
Abstract Coronavirus disease-2019 (COVID-19) caused by SARS-CoV-2 is an ongoing viral
pandemic marked by increased risk of thrombotic events. However, the role of platelets in …

[HTML][HTML] Is there a role for the ACE2 receptor in SARS‐CoV‐2 interactions with platelets?

RA Campbell, E Boilard, MT Rondina - Journal of Thrombosis and …, 2021 - Elsevier
There is an urgent need to understand the underlying mechanisms contributing to
thrombotic and inflammatory complications during COVID‐19. Data from independent …

[HTML][HTML] The ongoing enigma of SARS‐CoV‐2 and platelet interaction

Y Zaid, F Guessous - Research and practice in thrombosis and haemostasis, 2022 - Elsevier
Since the onset of the global pandemic of coronavirus disease 2019 (COVID‐19), there is an
urgent need to understand the pathogenesis of the common inflammatory and thrombotic …

Effect of aspirin on short-term outcomes in hospitalized patients with COVID-19

A Sahai, R Bhandari, M Godwin, T McIntyre… - Vascular …, 2021 - journals.sagepub.com
Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 is an ongoing viral
pandemic marked by increased risk of thrombotic events. However, the role of platelets in …

Crosstalk between Platelets and SARS-CoV-2: Implications in Thrombo-Inflammatory Complications in COVID-19

J Zhao, X Xu, Y Gao, Y Yu, C Li - International Journal of Molecular …, 2023 - mdpi.com
The SARS-CoV-2 virus, causing the devastating COVID-19 pandemic, has been reported to
affect platelets and cause increased thrombotic events, hinting at the possible bidirectional …

Thrombosis in Covid-19 and non-Covid-19 pneumonia: role of platelets

F Violi, V Cammisotto, P Pignatelli - Platelets, 2021 - Taylor & Francis
Platelets may be a target of bacteria and viruses, which can directly or indirectly activate
them so promoting thrombosis. In accordance with this, community-acquired pneumonia …

Platelets can associate with SARS-Cov-2 RNA and are hyperactivated in COVID-19

Y Zaid, F Puhm, I Allaeys, A Naya, M Oudghiri… - Circulation …, 2020 - Am Heart Assoc
Rationale: In addition to the overwhelming lung inflammation that prevails in coronavirus
disease 2019 (COVID-19), hypercoagulation and thrombosis contribute to the lethality of …

SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19

S Zhang, Y Liu, X Wang, L Yang, H Li, Y Wang… - Journal of hematology & …, 2020 - Springer
Background Critically ill patients diagnosed with COVID-19 may develop a pro-thrombotic
state that places them at a dramatically increased lethal risk. Although platelet activation is …

SARS-CoV-2 interacts with platelets and megakaryocytes via ACE2-independent mechanism

S Shen, J Zhang, Y Fang, S Lu, J Wu, X Zheng… - Journal of hematology & …, 2021 - Springer
Evidence suggests that platelets may directly interact with SARS-CoV-2, raising the concern
whether ACE2 receptor plays a role in this interaction. The current study showed that SARS …

SARS-CoV-2 infection is associated with a pro-thrombotic platelet phenotype

D Bongiovanni, M Klug, O Lazareva, S Weidlich… - Cell death & …, 2021 - nature.com
Abstract Novel coronavirus disease 2019 (COVID-19) is associated with a hypercoagulable
state, characterized by abnormal coagulation parameters and by increased incidence of …