Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances
made during the last 10-15 years in fields such as developmental biology, molecular …

Great progress has been made over the past 40 years in understanding the hazards of
exposure to a small number of developmental neurotoxicants. Lead, polychlorinated …

With the high cost and the long‐term assessment of developmental toxicity testing in
mammals, the vertebrate zebrafish has become a useful alternative model organism for high …

To anticipate to increased testing needs for reproductive toxicity and 3R approaches, we
studied zebrafish embryo/larva as an alternative for animal testing for developmental toxicity …

Given the ever‐increasing toxic exposure ubiquitously present in our environment as well as
emerging evidence that these exposures are hazardous to human health, the current rodent …

Abstract Dose-Response Assessment for Developmental Toxicity. I. Characterization of
Database and Determination of No Observed Adverse Effect Levels. Faustman, EM, Allen …

For hazard identification, classification, and labeling purposes, animal testing guidelines are
required by law to evaluate the developmental toxicity potential of new and existing …

With the high cost and slow pace of toxicity testing in mammals, the vertebrate zebrafish has
become a tractable model organism for high throughput toxicity testing. We present here a …

High-throughput test methods including molecular, cellular, and alternative species-based
assays that examine critical events of normal brain development are being developed for …

Background Current developmental toxicity testing adheres largely to protocols suggested in
1966 involving the administration of test compound to pregnant laboratory animals. After …