A RAPIDLY growing body of evidence indicates that volatile anesthetics protect myocardium
against reversible and irreversible ischemic injury. Identifying the mechanisms by which …

Preconditioning describes a very powerful endogenous mechanism by which the heart may
be protected against ischemia and reperfusion injury. Transient administration of a volatile …

Cardiac surgery and some noncardiac procedures are associated with a significant risk of
perioperative cardiac morbid events. Experimental data indicate that clinical concentrations …

Pharmacological preconditioning with volatile anesthetics, or anesthetic-induced
preconditioning (APC), is a phenomenon whereby a brief exposure to volatile anesthetic …

A steadily increasing number of investigations demonstrate that preconditioning with volatile
anesthetics attenuates the deleterious effects of myocardial ischemia and reperfusion injury …

Background The influence of anesthetic agents on the infarction process in the ischemic
myocardium is unclear. This study evaluated the effects of three intravenous and three …

This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in
both clinical and laboratory research and furthermore assesses possible cardiac side effects …

Background Volatile anesthetics induce pharmacological preconditioning in cardiac tissue.
The purpose of this study was to test whether volatile anesthetics mediate this effect by …

All volatile anesthetics have cardiac depressant effects that decrease myocardial oxygen
demand and may thus improve the myocardial oxygen balance during ischemia. Recent …

From the Anesthesia Service, the Clement J. Zablocki Veterans Affairs Medical Center,
Milwaukee, WI. This work was supported entirely by departmental funds. Address reprint …