Hepatic cholesterol transport and its role in non-alcoholic fatty liver disease and atherosclerosis

H Li, XH Yu, X Ou, XP Ouyang, CK Tang - Progress in lipid research, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …

Intracellular cholesterol transport

RE Soccio, JL Breslow - Arteriosclerosis, thrombosis, and vascular …, 2004 - Am Heart Assoc
Intracellular cholesterol transport is essential for the maintenance of cholesterol
homeostasis. Many aspects of cholesterol metabolism are well-known, including its …

Cholesterol transport system: an integrated cholesterol transport model involved in atherosclerosis

XH Yu, DW Zhang, XL Zheng, CK Tang - Progress in Lipid Research, 2019 - Elsevier
Atherosclerosis, the pathological basis of most cardiovascular disease (CVD), is closely
associated with cholesterol accumulation in the arterial intima. Excessive cholesterol is …

[HTML][HTML] Recent insights on the role of cholesterol in non-alcoholic fatty liver disease

G Arguello, E Balboa, M Arrese, S Zanlungo - Biochimica et Biophysica …, 2015 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of hepatic
histopathological changes ranging from non-inflammatory intracellular fat deposition to non …

Intracellular cholesterol synthesis and transport

Q Shi, J Chen, X Zou, X Tang - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Cholesterol homeostasis is related to multiple diseases in humans, including cardiovascular
disease, cancer, and neurodegenerative and hepatic diseases. The cholesterol levels in …

Transport of cholesterol

KR Norum, T Berg, P Helgerud… - Physiological …, 1983 - journals.physiology.org
. ur current model for cholesterol transport is summarized in Figure 10. In this figure we have
put together the various steps in cholesterol transport that were described previously in this …

Cholesterol and lipoprotein metabolism and atherosclerosis: recent advances in reverse cholesterol transport

HH Wang, G Garruti, M Liu, P Portincasa… - Annals of …, 2018 - medigraphic.com
Atherosclerosis is characterized by lipid accumulation, inflammatory response, cell death
and fibrosis in the arterial wall, and is a major pathological basis for ischemic coronary heart …

Molecular pathways underlying cholesterol homeostasis

MS Afonso, RM Machado, MS Lavrador, ECR Quintao… - Nutrients, 2018 - mdpi.com
Cholesterol is an essential molecule that exerts pleiotropic actions. Although its presence is
vital to the cell, its excess can be harmful and, therefore, sustaining cholesterol homeostasis …

Intestinal cholesterol transport proteins: an update and beyond

E Levy, S Spahis, D Sinnett, N Peretti… - Current opinion in …, 2007 - journals.lww.com
Intestinal cholesterol transport proteins: an update and bey... : Current Opinion in Lipidology
Intestinal cholesterol transport proteins: an update and beyond : Current Opinion in Lipidology …

Regulation of cholesterol homeostasis

MYM van der Wulp, HJ Verkade, AK Groen - Molecular and cellular …, 2013 - Elsevier
Hypercholesterolemia is an important risk factor for cardiovascular disease. It is caused by a
disturbed balance between cholesterol secretion into the blood versus uptake. The …