Machine learning for predicting neurodegenerative diseases in the general older population: a cohort study

GA Aguayo, L Zhang, M Vaillant, M Ngari… - BMC medical research …, 2023 - Springer
Background In the older general population, neurodegenerative diseases (NDs) are
associated with increased disability, decreased physical and cognitive function. Detecting …

Influence of medical domain knowledge on deep learning for Alzheimer's disease prediction

B Ljubic, S Roychoudhury, XH Cao, M Pavlovski… - Computer methods and …, 2020 - Elsevier
Background and objective Alzheimer's disease (AD) is the most common type of dementia
that can seriously affect a person's ability to perform daily activities. Estimates indicate that …

[HTML][HTML] Predicting Alzheimer's disease progression using deep recurrent neural networks

M Nguyen, T He, L An, DC Alexander, J Feng, BTT Yeo… - NeuroImage, 2020 - Elsevier
Early identification of individuals at risk of developing Alzheimer's disease (AD) dementia is
important for developing disease-modifying therapies. In this study, given multimodal AD …

Differences in cohort study data affect external validation of artificial intelligence models for predictive diagnostics of dementia-lessons for translation into clinical …

C Birkenbihl, MA Emon, H Vrooman, S Westwood… - EPMA Journal, 2020 - Springer
Artificial intelligence (AI) approaches pose a great opportunity for individualized, pre-
symptomatic disease diagnosis which plays a key role in the context of personalized …

Early prediction of Alzheimer's disease and related dementias using real‐world electronic health records

Q Li, X Yang, J Xu, Y Guo, X He, H Hu… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction This study aims to explore machine learning (ML) methods for early prediction
of Alzheimer's disease (AD) and related dementias (ADRD) using the real‐world electronic …

Machine learning for the prediction of cognitive impairment in older adults

W Li, L Zeng, S Yuan, Y Shang, W Zhuang… - Frontiers in …, 2023 - frontiersin.org
Objective The purpose of this study was to develop and validate a predictive model of
cognitive impairment in older adults based on a novel machine learning (ML) algorithm …

[HTML][HTML] Cox proportional hazard regression versus a deep learning algorithm in the prediction of dementia: an analysis based on periodic health examination

WJ Kim, JM Sung, D Sung, MH Chae… - JMIR medical …, 2019 - medinform.jmir.org
Background: With the increase in the world's aging population, there is a growing need to
prevent and predict dementia among the general population. The availability of national time …

AD-BERT: Using pre-trained language model to predict the progression from mild cognitive impairment to Alzheimer's disease

C Mao, J Xu, L Rasmussen, Y Li, P Adekkanattu… - Journal of Biomedical …, 2023 - Elsevier
Objective We develop a deep learning framework based on the pre-trained Bidirectional
Encoder Representations from Transformers (BERT) model using unstructured clinical notes …

Classifying the lifestyle status for Alzheimer's disease from clinical notes using deep learning with weak supervision

Z Shen, D Schutte, Y Yi, A Bompelli, F Yu… - BMC medical informatics …, 2022 - Springer
Background Since no effective therapies exist for Alzheimer's disease (AD), prevention has
become more critical through lifestyle status changes and interventions. Analyzing electronic …

Deep learning-based polygenic risk analysis for Alzheimer's disease prediction

X Zhou, Y Chen, FCF Ip, Y Jiang, H Cao, G Lv… - Communications …, 2023 - nature.com
Background The polygenic nature of Alzheimer's disease (AD) suggests that multiple
variants jointly contribute to disease susceptibility. As an individual's genetic variants are …