Work during the past 14 years has shown that mitochondria are the primary site for the
biosynthesis of iron–sulfur (Fe/S) clusters. In fact, it is this process that renders mitochondria …

Iron–sulfur (Fe/S) clusters belong to the most ancient protein cofactors in life, and fulfill
functions in electron transport, enzyme catalysis, homeostatic regulation, and sulfur …

Abstract Iron–sulfur (Fe–S) clusters are inorganic cofactors that are ubiquitous and essential.
Due to their chemical versatility, Fe–S clusters are implicated in a wide range of protein …

Iron–sulfur (Fe–S) clusters (ISCs) are versatile, ancient co-factors of proteins that are
involved in electron transport, enzyme catalysis and regulation of gene expression. The …

Iron–sulfur clusters (Fe–S) are one of the most ancient, ubiquitous and versatile classes of
metal cofactors found in nature. Proteins that contain Fe–S clusters constitute one of the …

Mitochondria play a key role in iron metabolism in that they synthesize heme, assemble iron–
sulfur (Fe/S) proteins, and participate in cellular iron regulation. Here, we review the latter …

Mitochondria are essential in most eukaryotes and are involved in numerous biological
functions including ATP production, cofactor biosyntheses, apoptosis, lipid synthesis, and …

Iron–sulfur clusters are ubiquitous inorganic co-factors that contribute to a wide range of cell
pathways including the maintenance of DNA integrity, regulation of gene expression and …

Iron–sulfur (Fe/S) clusters are important cofactors of numerous proteins involved in electron
transfer, metabolic and regulatory processes. In eukaryotic cells, known Fe/S proteins are …

Iron–sulfur (Fe/S) clusters (ISCs) are redox-active protein cofactors that their synthesis,
transfer, and insertion into target proteins require many components. Mitochondrial ISC …