Epidemiological data suggest that regular intake of isoflavones from soy reduces the
incidence of estrogen-dependent and aging-associated disorders, such as menopause …

Soy isoflavones have received considerable attention. Individuals with isoflavones‐rich diets
have significantly lower occurrences of cardiovascular disease, osteoporosis, and some …

The indigenous intestinal microflora are involved in a variety of processes within the human
body, and are important for maintaining host health. As such, interindividual differences in …

Equol, a microbial metabolite of daidzein, has been hypothesized as a clue to the
effectiveness of soy and its isoflavones but is excreted by only 33% of Caucasians. Microbial …

Isoflavones are found in leguminous plants, especially soybeans. They have a structural
similarity to natural estrogens, which enables them to bind to estrogen receptors and elicit …

Soy isoflavones have been suggested as an alternative treatment for managing
postmenopausal symptoms and promoting long-term health due to their structural similarity …

Equol is a metabolite of isoflavone daidzein and has an affinity to estrogen receptors.
Although equol is produced by intestinal bacteria, the association between the status of …

Hydroxy-3-(4′-hydroxyphenyl)-chroman (S-equol) is a specific end-metabolite formed in
the biotransformation of the dietary soy isoflavones daidzin and daidzein by intestinal …

Equol [7-hydroxy-3-(4′-hydroxyphenyl)-chroman] is a nonsteroidal estrogen of the
isoflavone class. It is exclusively a product of intestinal bacterial metabolism of dietary …

Intestinal conversion of the isoflavone daidzein to the bioactive equol is exclusively
catalyzed by gut bacteria, but a direct role in equol formation under in vivo conditions has …