Glioblastoma multiforme and medulloblastoma are the most frequent high-grade brain
tumors in adults and children, respectively. Standard therapies for these cancers are mainly …

New targets for brain tumor therapies may be identified by mutations that cause hereditary
microcephaly. Brain growth depends on the repeated proliferation of stem and progenitor …

Medulloblastoma (MB) and gliomas are the most frequent high-grade brain tumors (HGBT)
in children and adulthood, respectively. The general treatment for these tumors consists in …

The stem cells of neurogenesis and carcinogenesis share many properties, including
proliferative rate, an extensive replicative potential, the potential to generate different cell …

Medulloblastoma is the most common malignant brain tumor in children. This malignant
tumor of the cerebellum commonly affects children and is believed to arise from the …

The understanding and treatment of medulloblastoma, the most common childhood
malignant brain tumour, is rapidly evolving. Three complementary deep-sequencing studies …

This Special Issue focused on the current understanding of signaling pathways as well as
genetic and epigenetic features involved in the pathogenesis of brain tumors and other …

Introduction: Integrated genomics has significantly advanced our understanding of
medulloblastoma heterogeneity. It is now clear that it actually comprises at least four distinct …

Simple Summary In the last decade, medulloblastoma entered the molecular era, with
progressive advances in the knowledge of the molecular biology of this rare tumor. These …

Mitogen-activated protein kinase (MAPK) pathways are prominently involved in the onset
and progression of cancer. In particular, aberrant activation of MAPK pathways is mostly the …