AS Bassett, SW Scherer… - American Journal of …, 2010 - Am Psychiatric Assoc
Objective Structural variations of DNA, such as copy number variations (CNVs), are recognized to contribute both to normal genomic variability and to risk for human diseases …
GWC Tam, R Redon, NP Carter, SGN Grant - Biological psychiatry, 2009 - Elsevier
Schizophrenia is a major psychiatric disease with strong evidence of genetic risk factors. Recent studies based on genome-wide study of copy number variations (CNVs) have …
E Rees, JTR Walters, KD Chambert… - Human molecular …, 2014 - academic.oup.com
Large and rare copy number variants (CNVs) at several loci have been shown to increase risk for schizophrenia. Aiming to discover novel susceptibility CNV loci, we analyzed 6882 …
Copy number variants (CNVs) have been strongly implicated in the genetic etiology of schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk …
BACKGROUND: At least 10 large and rare recurrent DNA copy number variants (CNVs) have been identified as risk factors for schizophrenia and other neurodevelopmental …
D Grozeva, G Kirov, D Ivanov, IR Jones… - Archives of general …, 2010 - jamanetwork.com
Context Recent studies suggest that copy number variation in the human genome is extensive and may play an important role in susceptibility to disease, including …
JT Glessner, MP Reilly, CE Kim… - Proceedings of the …, 2010 - National Acad Sciences
Schizophrenia is a psychiatric disorder with onset in late adolescence and unclear etiology characterized by both positive and negative symptoms, as well as cognitive deficits. To …
K Ahn, N Gotay, TM Andersen, AA Anvari… - Molecular …, 2014 - nature.com
Copy number variants (CNVs) are risk factors in neurodevelopmental disorders, including autism, epilepsy, intellectual disability (ID) and schizophrenia. Childhood onset …
C Magri, E Sacchetti, M Traversa, P Valsecchi… - PloS one, 2010 - journals.plos.org
Genome-wide screenings for copy number variations (CNVs) in patients with schizophrenia have demonstrated the presence of several CNVs that increase the risk of developing the …