Near‐Infrared Upconversion Mesoporous Cerium Oxide Hollow Biophotocatalyst for Concurrent pH‐/H2O2‐Responsive O2‐Evolving Synergetic Cancer Therapy

C Yao, W Wang, P Wang, M Zhao, X Li… - Advanced …, 2018 - Wiley Online Library
Tumor hypoxia is typically presented in the central region of solid tumors, which is mainly
caused by an inadequate blood flow and oxygen supply. In the conventional treatment of …

Mesoporous cerium oxide-coated upconversion nanoparticles for tumor-responsive chemo-photodynamic therapy and bioimaging

T Jia, J Xu, S Dong, F He, C Zhong, G Yang, H Bi… - Chemical …, 2019 - pubs.rsc.org
Long-term tumor hypoxia has always been a huge obstacle for oxygen dependent
photodynamic therapy (PDT) and anticancer drug chemotherapy. Herein, a hollow …

A tumor pH-responsive autocatalytic nanoreactor as a H2O2 and O2 self-supplying depot for enhanced ROS-based chemo/photodynamic therapy

F Liu, T He, S Gong, M Shen, S Ma, X Huang, L Li… - Acta Biomaterialia, 2022 - Elsevier
Combining the internal force-driven chemodynamic therapy (CDT) and the external energy-
triggered photodynamic therapy (PDT) holds great promise to achieve an advanced …

Inhibiting tumor oxygen metabolism and simultaneously generating oxygen by intelligent upconversion nanotherapeutics for enhanced photodynamic therapy

D Wang, B Xue, TY Ohulchanskyy, Y Liu, A Yakovliev… - Biomaterials, 2020 - Elsevier
Hypoxia is one of the hallmarks of solid tumor, which heavily restricts the clinical cancer
therapy treatments, especially for the oxygen (O 2)-dependent photodynamic therapy (PDT) …

A mesoporous nanoenzyme derived from metal–organic frameworks with endogenous oxygen generation to alleviate tumor hypoxia for significantly enhanced …

D Wang, H Wu, WQ Lim, SZF Phua, P Xu… - Advanced …, 2019 - Wiley Online Library
Tumor hypoxia compromises the therapeutic efficiency of photodynamic therapy (PDT) as
the local oxygen concentration plays an important role in the generation of cytotoxic singlet …

Oxygen‐evolving mesoporous organosilica coated prussian blue nanoplatform for highly efficient photodynamic therapy of tumors

ZL Yang, W Tian, Q Wang, Y Zhao, YL Zhang… - Advanced …, 2018 - Wiley Online Library
Oxygen (O2) plays a critical role during photodynamic therapy (PDT), however, hypoxia is
quite common in most solid tumors, which limits the PDT efficacy and promotes the tumor …

Reductive surfactant-assisted one-step fabrication of a BiOI/BiOIO 3 heterojunction biophotocatalyst for enhanced photodynamic theranostics overcoming tumor …

W Zhen, Y Liu, X Jia, L Wu, C Wang, X Jiang - Nanoscale Horizons, 2019 - pubs.rsc.org
Inorganic biophotocatalysts with suitable size are greatly attractive in photodynamic therapy
(PDT) with enhanced permeability and retention effect and the capability to produce reactive …

An O2 Self‐Sufficient Biomimetic Nanoplatform for Highly Specific and Efficient Photodynamic Therapy

H Cheng, JY Zhu, SY Li, JY Zeng, Q Lei… - Advanced Functional …, 2016 - Wiley Online Library
Conventional oxygen‐dependent photodynamic therapy (PDT) has faced severe challenges
because of the non‐specificity of most available photosensitizers (PSs) and the hypoxic …

A two-photon excited O2-evolving nanocomposite for efficient photodynamic therapy against hypoxic tumor

RQ Li, C Zhang, BR Xie, WY Yu, WX Qiu, H Cheng… - Biomaterials, 2019 - Elsevier
This paper reported on a two-photon excited nanocomposite FCRH to overcome tumor
hypoxia for enhanced photodynamic therapy (PDT). Through modified by ruthenium (Ⅱ) …

Biomimetic O2-Evolving metal-organic framework nanoplatform for highly efficient photodynamic therapy against hypoxic tumor

S Gao, P Zheng, Z Li, X Feng, W Yan, S Chen, W Guo… - Biomaterials, 2018 - Elsevier
Improving the supply of O 2 and the circulation lifetime of photosensitizers for photodynamic
therapy (PDT) in vivo would be a promising approach to eliminate hypoxic tumors. Herein …