The emerging roles of miR-125b in cancers

Y Wang, G Zeng, Y Jiang - Cancer management and research, 2020 - Taylor & Francis
MicroRNAs (miRNAs) are endogenous, noncoding, single-stranded RNA molecules of 22
nucleotides in length. MiRNAs have both tumor-suppressive properties and oncogenic …

Diverse functions of miR-125 family in different cell contexts

YM Sun, KY Lin, YQ Chen - Journal of hematology & oncology, 2013 - Springer
MicroRNAs (miRNAs) are emerging as a novel class of non-coding RNA molecules that
regulate gene expression at a post-transcriptional level. More than 1000 miRNAs have been …

Good guy or bad guy: the opposing roles of microRNA 125b in cancer

J Banzhaf-Strathmann, D Edbauer - Cell communication and signaling, 2014 - Springer
MicroRNAs (miRNAs) are a class of non-coding RNAs that post-transcriptionally silence
target mRNAs. Dysregulation of miRNAs is a frequent event in several diseases, including …

MicroRNA-125 in immunity and cancer

JK Wang, Z Wang, G Li - Cancer letters, 2019 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that play a wide variety of critical roles in
different biological processes by post-transcriptionally regulating gene expression. They …

Progress on the relationship between miR-125 family and tumorigenesis

H Yin, Y Sun, X Wang, J Park, Y Zhang, M Li… - Experimental cell …, 2015 - Elsevier
Abstract miRNA-125 family, which is a highly conserved miRNA family throughout evolution,
is consist of miRNA-125a-3p, miRNA-125a-5p, miRNA-125b-1 and miRNA-125b-2. The …

Function of microRNA-145 and mechanisms underlying its role in malignant tumor diagnosis and treatment

D Ye, Z Shen, S Zhou - Cancer management and research, 2019 - Taylor & Francis
miRNAs are single-stranded small RNAs that do not encode proteins. They can combine
complementarily with the 3′-UTRs of target gene mRNA molecules to promote targeted …

MicroRNA-122 in human cancers: from mechanistic to clinical perspectives

M Faramin Lashkarian, N Hashemipour… - Cancer Cell …, 2023 - Springer
MicroRNAs (miRNAs) are endogenous short non-coding RNAs that can regulate the
expression of target genes post-transcriptionally and interact with mRNA-coding genes …

MicroRNA-125b promotes apoptosis by regulating the expression of Mcl-1, Bcl-w and IL-6R

J Gong, JP Zhang, B Li, C Zeng, K You, MX Chen… - Oncogene, 2013 - nature.com
The microRNA miR-125b is multi-faceted, with the ability to function as a tumor suppressor
or an oncogene, depending on the cellular context. To date, the pro-apoptotic role of miR …

miR-125a-5p inhibits cell proliferation and induces apoptosis in colon cancer via targeting BCL2, BCL2L12 and MCL1

Z Tong, N Liu, L Lin, X Guo, D Yang, Q Zhang - Biomedicine & …, 2015 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that function as regulators of gene
expression. MiR-125 is a family of miRNAs that have been shown to be involved in various …

MicroRNA‐124: an emerging therapeutic target in cancer

X Jia, X Wang, X Guo, J Ji, G Lou, J Zhao… - Cancer …, 2019 - Wiley Online Library
MicroRNAs (miRNAs) are noncoding single‐stranded RNAs, approximately 20‐24
nucleotides in length, known as powerful posttranscriptional regulators. miRNAs play …