Seasonal human influenza is a serious respiratory infection caused by influenza viruses that
can be found all over the world. Type A influenza is a contagious viral infection that, if left …

The evolution of drug-resistant viral strains following natural acquisition of resistance
mutations is a major obstacle to antiviral therapy. Besides the improper prescription of the …

Neuraminidase (NA) is a membrane surface antigen which helps in the release of influenza
viruses from the host cells after replication. Anti-influenza drugs such as zanamivir bind with …

The genetic mutability of the influenza virus leads to the existence of drug-resistant strains
which is dangerous, particularly with the lingering coronavirus disease (COVID-19). This …

The Influenza A virus is a great threat for human health, while various subtypes of the virus
made it difficult to develop drugs. With the development of state-of-art computational …

Abstract The influenza A (H1N1) virus, also known as swine flu is a leading cause of
morbidity and mortality since 2009. There is a need to explore novel anti-viral drugs for …

Influenza type A is considered as a severe public health concern. The mechanism of drugs
applied for the control of this virus depends on two surface glycoproteins with antigenic …

As a new strain of virus emerged in 2013, avian influenza A (H7N9) virus is a threat to the
public health, due to its high lethality and pathogenicity. Furthermore, H7N9 has already …

Background This research provides a comprehensive analysis of QSAR modeling
performed on 25 aryl sulfonamide derivatives to predict their effective concentration (EC 50) …

Neuraminidase (NA) enzyme is one of the valid targets against influenza viruses. With this in
mind, the pharmacophoric space of influenza NA was explored using three sets of diverse …