Aortic stenosis (AS) affects about 1.5 million people in the United States and is associated
with a 5-year survival rate of 20% if untreated. In these patients, aortic valve replacement is …

Preclinical models of aortic stenosis can induce left ventricular pressure overload and
coarsely control the severity of aortic constriction. However, they do not recapitulate the …

Precision medicine is a new frontier in healthcare that uses scientific methods to customize
medical treatment to the individual genes, anatomy, physiology, and lifestyle of each person …

Computed tomography (CT) provides high-resolution images of the aortic valve with clear
localization of calcium deposition. Three-dimensional (3D) stereolithographic printing can …

Minimally invasive surgeries have numerous advantages, yet complications may arise from
limited knowledge about the anatomical site targeted for the delivery of therapy …

Minimally invasive surgery (MIS) during cardiovascular interventions reduces trauma and
enables the treatment of high-risk patients who were initially denied surgery. However …

Aortic stenosis is an acute and chronic cardiovascular disease that often coexists with other
complex valvular, ventricular and vascular diseases (C3VD). Transcatheter aortic valve …

Aortic stenosis (AS) is the most prevalent heart valve disease in western countries that
poses a significant public health challenge due to the lack of a medical treatment to prevent …

Background—3D stereolithographic printing can be used to convert high-resolution
computed tomography images into life-size physical models. We sought to apply 3D printing …

The hemodynamics in the aorta as well as the durability of aortic valve prostheses vary
greatly between different types of devices. Although placement and sizing of surgical aortic …