Abstract α-Tocopherol (α-T) is a required dietary nutrient for humans and thus is a vitamin.
This narrative review focuses on vitamin E structures, functions, biological determinants and …

Vitamin E (α-tocopherol) was discovered nearly 100 years ago because it was required to
prevent fetal resorption in pregnant, vitamin E-deficient rats fed lard-containing diets that …

Alpha-tocopherol, one of the eight isoforms of vitamin E, is the most potent fat-soluble
antioxidant known in nature. For years, it was thought that α-tocopherol only functioned as a …

More than 80 years after the discovery of the essentiality of vitamin E for mammals, the
molecular basis of its action is still an enigma. From the eight different forms of vitamin E …

Some 80 years after its discovery, vitamin E has experienced a renaissance which is as
surprising as it is trivial. Although vitamin E is essential for reproduction, in rats at least, and …

It is estimated that> 90% of Americans do not consume sufficient dietary vitamin E, as α-
tocopherol, to meet estimated average requirements. What are the adverse consequences …

Nearly after one century of research and thousands of publications, the physiological
function (s) of vitamin E remain unclear. Available evidence suggests a role in cell …

During the last 90 years since the discovery of vitamin E, research has focused on different
properties of this molecule, the focus often depending on the specific techniques and …

Dietary and supplemental vitamin E is absorbed and delivered to the liver, but of the various
antioxidants with vitamin E activity, only α-tocopherol is preferentially recognized by the α …

Vitamin E is indispensible for reproduction in female rats. In humans, vitamin E deficiency
primarily causes neurologic dysfunctions, but the underlying molecular mechanisms are …