Connecting Cryptococcal Meningitis and Gut Microbiome

Y Ma, L Yang, M Jiang, X Zhao, P Xue - International Journal of Molecular …, 2023 - mdpi.com
Fungal pathogens of the Cryptococcus neoformans species complex (C. neoformans SC)
are a major cause of fungal meningitis in immunocompromised individuals. As with other …

Gut microbiota associated with cryptococcal meningitis and dysbiosis caused by anti-fungal treatment

H Li, L Zhang, K Zhang, Y Huang, Y Liu, X Lu… - Frontiers in …, 2023 - frontiersin.org
The gut microbiota is a dynamic and highly diverse microbial ecosystem that affects many
aspects of the host's physiology. An improved understanding of the gut microbiota could …

Characterization of host response to Cryptococcus neoformans through quantitative proteomic analysis of cryptococcal meningitis co-infected with HIV

LDN Selvan, SK Sreenivasamurthy, S Kumar… - Molecular …, 2015 - pubs.rsc.org
Cryptococcal meningitis is the most common opportunistic fungal infection causing morbidity
and mortality (> 60%) in HIV-associated immunocompromised individuals caused by …

Comparative miRNA transcriptomics of macaques and mice reveals MYOC is an inhibitor for Cryptococcus neoformans invasion into the brain

H Li, X Han, W Du, Y Meng, Y Li, T Sun… - Emerging Microbes & …, 2022 - Taylor & Francis
Cryptococcal meningoencephalitis (CM) is emerging as an infection in HIV/AIDS patients
shifted from primarily ARTnaive to ART-experienced individuals, as well as patients with …

Genetic Factors and Genotype-Environment Interactions Contribute to Variation in Melanin Production in the Fungal Pathogen Cryptococcus neoformans

H Samarasinghe, D Aceituno-Caicedo, M Cogliati… - Scientific reports, 2018 - nature.com
Cryptococcosis is a common opportunistic fungal infection that often disseminates into the
central nervous system, leading to meningitis. Production of melanin pigments during …

The Environmental Effects on Virulence Factors and the Antifungal Susceptibility of Cryptococcus neoformans

M Momin, G Webb - International Journal of Molecular Sciences, 2021 - mdpi.com
Cryptococcus neoformans is a facultative intracellular pathogen responsible for fungal
meningoencephalitis primarily in immunocompromised individuals. It has become evident …

Molecular mechanisms of cryptococcal meningitis

TB Liu, DS Perlin, C Xue - Virulence, 2012 - Taylor & Francis
Fungal meningitis is a serious disease caused by a fungal infection of the central nervous
system (CNS) mostly in individuals with immune system deficiencies. Fungal meningitis is …

Dynamics of Cryptococcus neoformans-macrophage interactions reveal that fungal background influences outcome during cryptococcal meningoencephalitis in …

A Alanio, M Desnos-Ollivier, F Dromer - MBio, 2011 - Am Soc Microbiol
Cryptococcosis is a multifaceted fungal infection with variable clinical presentation and
outcome. As in many infectious diseases, this variability is commonly assigned to host …

The Cryptococcus neoformans transcriptome at the site of human meningitis

Y Chen, DL Toffaletti, JL Tenor, AP Litvintseva, C Fang… - MBio, 2014 - Am Soc Microbiol
Cryptococcus neoformans is the leading cause of fungal meningitis worldwide. Previous
studies have characterized the cryptococcal transcriptome under various stress conditions …

Innate immune evasion strategies against Cryptococcal meningitis caused by Cryptococcus neoformans

CL Yang, J Wang, LL Zou - Experimental and …, 2017 - spandidos-publications.com
As an infectious fungus that affects the respiratory tract, Cryptococcus neoformans (C.
neoformans) commonly causes asymptomatic pulmonary infection. C. neoformans may …