[PDF][PDF] The virulence system of Porphyromonas gingivalis: Genes, mechanism and potential role of gingipains inhibitors.

MA Sa'ad, R Kavitha, NK Fuloria, S Fuloria… - Malaysian Journal of …, 2021 - researchgate.net
The oral microbiome comprises several hundreds of bacterial species that contribute to
periodontitis, the most complex polymicrobial inflammatory disorder. Porphyromonas …

Molecular genetics of Porphyromonas gingivalis: gingipains and other virulence factors

K Nakayama - Current Protein and Peptide Science, 2003 - ingentaconnect.com
Porphyromonas gingivalis is a black-pigmented anaerobic gram-negative bacterium that is a
major pathogen of chronic adult periodontitis, an inflammatory disease of toothsupporting …

[HTML][HTML] Strategies for targeting the gingipain secretion system of Porphyromonas gingivalis

K Saiki, K Konishi - Journal of Oral Biosciences, 2012 - Elsevier
Porphyromonas gingivalis is considered the most important etiologic agent in chronic
periodontitis. P. gingivalis secretes several proteases that promote disease progression by …

Roles of Porphyromonas gingivalis and its virulence factors in periodontitis

W Xu, W Zhou, H Wang, S Liang - Advances in protein chemistry and …, 2020 - Elsevier
Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival
inflammation and bone loss. Periodontitis is associated with various systemic diseases …

[HTML][HTML] Transcriptional profiling of human smooth muscle cells infected with gingipain and fimbriae mutants of Porphyromonas gingivalis

B Zhang, A Sirsjö, H Khalaf, T Bengtsson - Scientific Reports, 2016 - nature.com
Porphyromonas gingivalis (P. gingivalis) is considered to be involved in the development of
atherosclerosis. However, the role of different virulence factors produced by P. gingivalis in …

Strategies for the inhibition of gingipains for the potential treatment of periodontitis and associated systemic diseases

I Olsen, J Potempa - Journal of oral microbiology, 2014 - Taylor & Francis
Gingipains are the major virulence factors of Porphyromonas gingivalis, the main
periodontopathogen. It is expected that inhibition of gingipain activity in vivo could prevent or …

Effect of Inactivation of the Arg- and/or Lys-Gingipain Gene on Selected Virulence and Physiological Properties of Porphyromonas gingivalis

D Grenier, S Roy, F Chandad, P Plamondon… - Infection and …, 2003 - Am Soc Microbiol
Proteolytic enzymes produced by Porphyromonas gingivalis are thought to play critical roles
in the pathogenesis of periodontitis. The aim of this study was to investigate the effect of …

Molecular strategies underlying Porphyromonas gingivalis virulence

IL Silva, E Cascales - Journal of Molecular Biology, 2021 - Elsevier
The anaerobic Gram-negative bacterium Porphyromonas gingivalis is considered the
keystone of periodontitis diseases, a set of inflammatory conditions that affects the tissues …

Analysis of Major Virulence Factors in Porphyromonas gingivalis under Various Culture Temperatures Using Specific Antibodies

Y Murakami, T Masuda, M Imai, J Iwami… - Microbiology and …, 2004 - Wiley Online Library
Porphyromonas gingivalis is implicated in the occurrence of adult periodontitis. We have
previously identified major outer membrane proteins from P. gingivalis, which include …

[PDF][PDF] Molecular pathogenesis of bacteria-induced periodontitis

I Park, H Gu, KK Park - Int J Clin Exp Med, 2018 - e-century.us
Periodontitis, one of the most common inflammatory diseases, is induced by bacteria such
as Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola. Of these, P …