[HTML][HTML] Application of humanized zebrafish model in the suppression of SARS-CoV-2 spike protein induced pathology by tri-herbal medicine coronil via cytokine …

A Balkrishna, SK Solleti, S Verma, A Varshney - Molecules, 2020 - mdpi.com
Zebrafish has been a reliable model system for studying human viral pathologies. SARS-
CoV-2 viral infection has become a global chaos, affecting millions of people. There is an …

Coronil, a tri-herbal formulation, attenuates spike-protein-mediated SARS-CoV-2 viral entry into human alveolar epithelial cells and pro-inflammatory cytokines …

A Balkrishna, S Haldar, H Singh, P Roy… - Journal of …, 2021 - Taylor & Francis
Purpose: Coronil is a tri-herbal formulation containing extracts from Withania somnifera,
Tinospora cordifolia, and Ocimum sanctum. Recently, it was shown that Coronil rescued …

[HTML][HTML] Giloy Ghanvati (Tinospora cordifolia (Willd.) Hook. f. and Thomson) Reversed SARS-CoV-2 Viral Spike-Protein Induced Disease Phenotype in the …

A Balkrishna, L Khandrika, A Varshney - Frontiers in pharmacology, 2021 - frontiersin.org
The current Severe Acute Respiratory Syndrome disease caused by Coronavirus-2 (SARS-
CoV-2) has been a serious strain on the healthcare infrastructure mainly due to the lack of a …

[HTML][HTML] Honeysuckle (Lonicera japonica) and Huangqi (Astragalus membranaceus) Suppress SARS-CoV-2 Entry and COVID-19 Related Cytokine Storm in Vitro

YC Yeh, LH Doan, ZY Huang, LW Chu… - Frontiers in …, 2022 - frontiersin.org
COVID-19 is threatening human health worldwide but no effective treatment currently exists
for this disease. Current therapeutic strategies focus on the inhibition of viral replication or …

[HTML][HTML] Eugenol, a component of holy basil (Tulsi) and common spice clove, inhibits the interaction between SARS-CoV-2 spike S1 and ACE2 to induce therapeutic …

RK Paidi, M Jana, S Raha, M McKay, M Sheinin… - Journal of Neuroimmune …, 2021 - Springer
Abstract Spike S1 of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
binds to angiotensin-converting enzyme 2 (ACE2) on host cells to enter the cell and initiate …

[HTML][HTML] Potential immunomodulatory properties of biologically active components of spices against SARS-CoV-2 and Pan β-Coronaviruses

S Sengupta, D Bhattacharyya, G Kasle… - Frontiers in Cellular …, 2021 - frontiersin.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced COVID-19
has emerged as a defining global health crisis in current times. Data from the World Health …

Citrus fruits are rich in flavonoids for immunoregulation and potential targeting ACE2

L Cheng, W Zheng, M Li, J Huang, S Bao, Q Xu, Z Ma - 2020 - preprints.org
The most recent outbreak of 2019 novel coronavirus, named as COVID-19, caused
pneumonia epidemic in Wuhan with 2,121 deaths cases as of February 20 th 2020 …

[HTML][HTML] Citrus fruits are rich in flavonoids for immunoregulation and potential targeting ACE2

W Liu, W Zheng, L Cheng, M Li, J Huang, S Bao… - Natural Products and …, 2022 - Springer
The most recent outbreak of 2019 novel coronavirus, named as COVID-19, caused
pneumonia epidemic in Wuhan with 2121 deaths cases as of February 20th 2020 …

[HTML][HTML] Roles of existing drug and drug targets for COVID-19 management

AG Ayele, EF Enyew, ZD Kifle - Metabolism Open, 2021 - Elsevier
In December 2019, a highly transmissible, pneumonia epidemic caused by a novel
coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), erupted in …

Nanocurcumin potently inhibits SARS-CoV-2 spike protein-induced cytokine storm by deactivation of MAPK/NF-κB signaling in epithelial cells

VK Sharma, Prateeksha, SP Singh… - ACS Applied Bio …, 2022 - ACS Publications
Interleukin-mediated deep cytokine storm, an aggressive inflammatory response to SARS-
CoV-2 virus infection in COVID-19 patients, is correlated directly with lung injury, multi-organ …