SERS Signature of SARS-CoV-2 in Saliva and Nasopharyngeal Swabs: Towards Perspective COVID-19 Point-of-Care Diagnostics

SM Berus, AB Nowicka, J Wieruszewska… - International Journal of …, 2023 - mdpi.com
In this study, the intrinsic surface-enhanced Raman spectroscopy (SERS)-based approach
coupled with chemometric analysis was adopted to establish the biochemical fingerprint of …

Machine Learning for COVID-19 Determination Using Surface-Enhanced Raman Spectroscopy

TR Szymborski, SM Berus, AB Nowicka, G Słowiński… - Biomedicines, 2024 - mdpi.com
The rapid, low cost, and efficient detection of SARS-CoV-2 virus infection, especially in
clinical samples, remains a major challenge. A promising solution to this problem is the …

On-site detection of SARS-CoV-2 antigen by deep learning-based surface-enhanced Raman spectroscopy and its biochemical foundations

J Huang, J Wen, M Zhou, S Ni, W Le, G Chen… - Analytical …, 2021 - ACS Publications
A rapid, on-site, and accurate SARS-CoV-2 detection method is crucial for the prevention
and control of the COVID-19 epidemic. However, such an ideal screening technology has …

[HTML][HTML] A non-invasive ultrasensitive diagnostic approach for COVID-19 infection using salivary label-free SERS fingerprinting and artificial intelligence

V Karunakaran, MM Joseph, I Yadev, H Sharma… - … of Photochemistry and …, 2022 - Elsevier
Clinical diagnostics for SARS-CoV-2 infection usually comprises the sampling of throat or
nasopharyngeal swabs that are invasive and create patient discomfort. Hence, saliva is …

Label-free SARS-CoV-2 Detection Platform Based on Surface-enhanced Raman Spectroscopy with Support Vector Machine Spectral Pattern Recognition

T Li, S Srivastava, J Liu, F Li, Y Kim… - Engineered …, 2023 - espublisher.com
We introduce a biosensing platform combining surface-enhanced Raman spectroscopy
(SERS) and machine learning for combating COVID-19 and potentially future occurrence of …

The Label-Free Detection and Identification of SARS-CoV-2 Using Surface-Enhanced Raman Spectroscopy and Principal Component Analysis

L Zhou, A Vestri, V Marchesano, M Rippa, D Sagnelli… - Biosensors, 2023 - mdpi.com
The World Health Organization (WHO) declared in a May 2023 announcement that the
COVID-19 illness is no longer categorized as a Public Health Emergency of International …

Ultrafast Detection of SARS-CoV-2 Spike protein (S) and receptor-binding domain (RBD) in Saliva using surface-enhanced Raman spectroscopy

MB Abdullah, C Dab, M Almalki, A Alnaim, A Abuzir… - Applied Sciences, 2022 - mdpi.com
Controlling contagious diseases necessitates using diagnostic techniques that can detect
infection in the early stages. Although different diagnostic tools exist, there are still …

Saliva-based detection of COVID-19 infection in a real-world setting using reagent-free Raman spectroscopy and machine learning

K Ember, F Daoust, M Mahfoud… - … of biomedical optics, 2022 - spiedigitallibrary.org
Significance: The primary method of COVID-19 detection is reverse transcription polymerase
chain reaction (RT-PCR) testing. PCR test sensitivity may decrease as more variants of …

COVID-19 salivary Raman fingerprint: innovative approach for the detection of current and past SARS-CoV-2 infections

C Carlomagno, D Bertazioli, A Gualerzi, S Picciolini… - Scientific reports, 2021 - nature.com
The pandemic of COVID-19 is continuously spreading, becoming a worldwide emergency.
Early and fast identification of subjects with a current or past infection must be achieved to …

A combined approach of MALDI-TOF mass spectrometry and multivariate analysis as a potential tool for the detection of SARS-CoV-2 virus in nasopharyngeal swabs

MF Rocca, JC Zintgraff, ME Dattero, LS Santos… - Journal of Virological …, 2020 - Elsevier
Coronavirus disease 2019, known as COVID-19, is caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). The early, sensitive and specific detection of SARS …