Transporters in the human liver play a major role in the clearance of endo-and xenobiotics.
Apical (canalicular) transporters extrude compounds to the bile, while basolateral …

During the COVID-19 pandemic, several repurposed drugs have been proposed to alleviate
the major health effects of the disease. These drugs are often applied with analgesics or non …

Drug‐drug interaction potentials of ensitrelvir, a novel oral inhibitor of 3C‐like protease of
severe acute respiratory syndrome coronavirus 2, for drug transporters were evaluated by in …

Equilibrative nucleoside transporters (ENTs) are present at the blood-testis barrier (BTB),
where they can facilitate antiviral drug disposition to eliminate a sanctuary site for viruses …

Numerous drugs are currently under accelerated clinical investigation for the treatment of
coronavirus disease 2019 (COVID‐19); however, well‐established safety and efficacy data …

The ongoing pandemic of severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2)
and subsequently, coronavirus disease 2019 (COVID‐19), has led to the deaths of over 6.1 …

Background The antiviral drug molnupiravir is an orally bioavailable prodrug of the
nucleoside analog β-D-N4-hydroxycytidine (NHC), which is used to treat coronavirus …

Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide. Effective treatments against …

Telaprevir is a new, direct-acting antiviral drug that has been approved for the treatment of
chronic hepatitis C viral infection. First data on drug–drug interactions with co-medications …

COVID-19 is announced as a global pandemic in 2020. Its mortality and morbidity rate are
rapidly increasing, with limited medications. The emergent outbreak of COVID-19 prompted …